Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ADQ03633.1Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides. (232 aa)    
Predicted Functional Partners:
ADQ05678.1
KEGG: ate:Athe_2606 thioredoxin-disulfide reductase; manually curated; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase.
  
 
 0.915
ADQ05160.1
PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; KEGG: ate:Athe_1898 alkyl hydroperoxide reductase/thiol specific antioxidant/Mal allergen.
  
 0.868
dnaK
Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.
   
 
 0.860
tpiA
Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family.
  
 
 0.859
ADQ05702.1
TIGRFAM: redox-active disulfide protein 2; KEGG: ate:Athe_2641 redox-active disulfide protein 2.
  
 0.847
ADQ04921.1
Thioredoxin; KEGG: csc:Csac_1727 thioredoxin; TIGRFAM: thioredoxin; PFAM: Thioredoxin domain-containing protein; Belongs to the thioredoxin family.
  
 
 0.727
ADQ03708.1
Ferric uptake regulator, Fur family; PFAM: ferric-uptake regulator; KEGG: csc:Csac_2429 ferric uptake regulator family protein; Belongs to the Fur family.
  
  
 0.674
ADQ04620.1
KEGG: ate:Athe_1266 pyruvate kinase; TIGRFAM: pyruvate kinase; PFAM: Pyruvate kinase barrel; Pyruvate kinase alpha/beta; PEP-utilising protein mobile region.
   
 
 0.654
ADQ04055.1
KEGG: ate:Athe_0605 hypothetical protein.
  
    0.640
ADQ04262.1
KEGG: ate:Athe_0839 phosphodiesterase, MJ0936 family; TIGRFAM: phosphodiesterase, MJ0936 family; PFAM: metallophosphoesterase.
   
 
 0.632
Your Current Organism:
Caldicellulosiruptor owensensis
NCBI taxonomy Id: 632518
Other names: C. owensensis OL, Caldicellulosiruptor owensensis DSM 13100, Caldicellulosiruptor owensensis OL, Caldicellulosiruptor owensensis str. OL, Caldicellulosiruptor owensensis strain OL
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