Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ADQ03668.1KEGG: ate:Athe_0102 two component transcriptional regulator, AraC family; PFAM: response regulator receiver; helix-turn-helix- domain containing protein AraC type; SMART: Helix-turn-helix, AraC domain; response regulator receiver. (519 aa)    
Predicted Functional Partners:
ADQ03669.1
KEGG: ate:Athe_0103 signal transduction histidine kinase, LytS; PFAM: histidine kinase internal region; histidine kinase HAMP region domain protein; ATP-binding region ATPase domain protein; SMART: histidine kinase HAMP region domain protein.
 
 
  0.961
ADQ04273.1
Integral membrane sensor signal transduction histidine kinase; KEGG: ate:Athe_0852 putative sensor with HAMP domain; PFAM: histidine kinase internal region; histidine kinase HAMP region domain protein; ATP-binding region ATPase domain protein; SMART: histidine kinase HAMP region domain protein.
 
 
 0.832
ADQ04048.1
Integral membrane sensor signal transduction histidine kinase; KEGG: ate:Athe_0599 putative sensor with HAMP domain; PFAM: histidine kinase internal region; histidine kinase HAMP region domain protein; ATP-binding region ATPase domain protein; SMART: histidine kinase HAMP region domain protein.
 
 
 0.831
ADQ03667.1
KEGG: ate:Athe_0101 monosaccharide-transporting ATPase.
 
     0.821
ADQ05610.1
Signal transduction histidine kinase, LytS; PFAM: histidine kinase internal region; ATP-binding region ATPase domain protein; KEGG: ate:Athe_2372 histidine kinase internal region.
 
 
 0.746
ADQ04057.1
Integral membrane sensor signal transduction histidine kinase; KEGG: pjd:Pjdr2_0906 histidine kinase; PFAM: histidine kinase internal region; histidine kinase HAMP region domain protein; ATP-binding region ATPase domain protein; SMART: histidine kinase HAMP region domain protein.
 
 
  0.737
ADQ04596.1
KEGG: ate:Athe_1242 hypothetical protein.
  
     0.618
ADQ05212.1
PFAM: Fibronectin type III domain protein; KEGG: ate:Athe_1944 fibronectin type III domain protein.
  
     0.599
ADQ04160.1
KEGG: ate:Athe_0715 hypothetical protein.
  
     0.589
ADQ03728.1
PFAM: extracellular solute-binding protein family 1; KEGG: ate:Athe_0181 extracellular solute-binding protein family 1.
  
   
 0.582
Your Current Organism:
Caldicellulosiruptor owensensis
NCBI taxonomy Id: 632518
Other names: C. owensensis OL, Caldicellulosiruptor owensensis DSM 13100, Caldicellulosiruptor owensensis OL, Caldicellulosiruptor owensensis str. OL, Caldicellulosiruptor owensensis strain OL
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