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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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[Homology]
Score
ADQ03697.1Phosphoenolpyruvate-protein phosphotransferase; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr). (554 aa)    
Predicted Functional Partners:
ADQ03696.1
Phosphotransferase system, phosphocarrier protein HPr; KEGG: ate:Athe_0150 phosphocarrier, HPr family; TIGRFAM: phosphocarrier, HPr family; PFAM: phosphoryl transfer system HPr.
 
 0.999
ADQ03820.1
Phosphotransferase system, phosphocarrier protein HPr; KEGG: ate:Athe_0323 phosphocarrier, HPr family; TIGRFAM: phosphocarrier, HPr family; PFAM: phosphoryl transfer system HPr.
 
 0.998
ADQ03695.1
KEGG: ate:Athe_0149 PTS system, fructose subfamily, IIC subunit; TIGRFAM: PTS system, fructose subfamily, IIC subunit; PTS system, fructose-specific, IIB subunnit; PFAM: phosphotransferase system EIIC.
 
  
 0.996
ADQ04635.1
KEGG: ate:Athe_1281 hypothetical protein.
  
 0.987
ADQ03693.1
KEGG: ate:Athe_0147 1-phosphofructokinase; TIGRFAM: 1-phosphofructokinase; PFAM: PfkB domain protein; Belongs to the carbohydrate kinase PfkB family. LacC subfamily.
 
  
 0.915
ADQ03694.1
KEGG: ate:Athe_0148 putative PTS IIA-like nitrogen-regulatory protein PtsN; TIGRFAM: PTS system, fructose subfamily, IIA subunit; PFAM: phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2.
 
   
 0.886
tpiA
Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family.
  
  
 0.656
hprK
HPr kinase; Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr). The two antagonistic activities of HprK/P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (gluc [...]
 
   
 0.633
ADQ04620.1
KEGG: ate:Athe_1266 pyruvate kinase; TIGRFAM: pyruvate kinase; PFAM: Pyruvate kinase barrel; Pyruvate kinase alpha/beta; PEP-utilising protein mobile region.
  
  
 0.536
ADQ03692.1
KEGG: ate:Athe_0146 transcriptional regulator, DeoR family; PFAM: regulatory protein DeoR; SMART: regulatory protein DeoR.
  
  
 0.496
Your Current Organism:
Caldicellulosiruptor owensensis
NCBI taxonomy Id: 632518
Other names: C. owensensis OL, Caldicellulosiruptor owensensis DSM 13100, Caldicellulosiruptor owensensis OL, Caldicellulosiruptor owensensis str. OL, Caldicellulosiruptor owensensis strain OL
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