Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
ADQ03733.1PFAM: esterase; KEGG: ate:Athe_0186 putative esterase. (266 aa)    
Predicted Functional Partners:
ADQ03732.1
Endo-1,4-beta-xylanase; PFAM: glycoside hydrolase family 10; KEGG: ate:Athe_0185 endo-1,4-beta-xylanase; SMART: glycoside hydrolase family 10.
       0.618
ADQ03729.1
Glycoside hydrolase family 43; KEGG: csc:Csac_2411 carbohydrate-binding family 6 protein; PFAM: glycoside hydrolase family 43; Carbohydrate-binding CenC domain protein; Carbohydrate binding family 6; SMART: cellulose binding type IV.
 
    0.582
ADQ04920.1
PFAM: protein of unknown function DUF156; KEGG: ate:Athe_1624 protein of unknown function DUF156.
  
  
 0.578
ADQ05048.1
PFAM: protein of unknown function DUF156; KEGG: ate:Athe_1759 protein of unknown function DUF156.
  
  
 0.578
tpiA
Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family.
   
 
 0.573
ADQ03994.1
PFAM: lipolytic protein G-D-S-L family; KEGG: ate:Athe_0553 lipolytic protein G-D-S-L family.
  
   
 0.563
ADQ03731.1
KEGG: ate:Athe_0184 xylan 1,4-beta-xylosidase; PFAM: glycoside hydrolase family 39.
       0.549
ADQ03734.1
PFAM: glycoside hydrolase family 39; KEGG: csc:Csac_2404 glycoside hydrolase family protein.
       0.523
ADQ04262.1
KEGG: ate:Athe_0839 phosphodiesterase, MJ0936 family; TIGRFAM: phosphodiesterase, MJ0936 family; PFAM: metallophosphoesterase.
  
  
 0.509
ADQ03965.1
KEGG: ate:Athe_0524 aconitate hydratase; TIGRFAM: aconitate hydratase; homoaconitate hydratase family protein; PFAM: aconitate hydratase domain-containing protein.
    
 
 0.508
Your Current Organism:
Caldicellulosiruptor owensensis
NCBI taxonomy Id: 632518
Other names: C. owensensis OL, Caldicellulosiruptor owensensis DSM 13100, Caldicellulosiruptor owensensis OL, Caldicellulosiruptor owensensis str. OL, Caldicellulosiruptor owensensis strain OL
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