Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
birAbiotin/acetyl-CoA-carboxylase ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family. (314 aa)    
Predicted Functional Partners:
bioB
Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family.
  
 
 0.962
ADQ05708.1
KEGG: ate:Athe_2647 radical SAM domain protein; PFAM: Radical SAM domain protein; biotin and thiamin synthesis associated; SMART: Elongator protein 3/MiaB/NifB.
  
 
 0.962
ADQ03879.1
PFAM: peptidase M22 glycoprotease; KEGG: ate:Athe_0445 peptidase M22 glycoprotease.
 
    0.917
ADQ05638.1
PFAM: CMP/dCMP deaminase zinc-binding; KEGG: ate:Athe_2395 CMP/dCMP deaminase zinc-binding.
  
    0.916
ADQ05519.1
PFAM: biotin/lipoyl attachment domain-containing protein; KEGG: csc:Csac_2483 biotin/lipoyl attachment domain-containing protein.
 
  
 0.901
ADQ03755.1
TIGRFAM: dihydropteroate synthase; KEGG: ate:Athe_0210 dihydropteroate synthase; PFAM: dihydropteroate synthase DHPS.
     
 0.885
ADQ04670.1
PFAM: carboxyl transferase; KEGG: ate:Athe_1316 carboxyl transferase.
 
 
 0.881
ADQ03757.1
TIGRFAM: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase; KEGG: ate:Athe_0212 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase; PFAM: 78-dihydro-6-hydroxymethylpterin-pyrophosphokinase HPPK.
  
  
 0.872
coaX
Transcriptional activator, Baf family; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
  
    0.856
ADQ03753.1
PFAM: protein of unknown function DUF1284; KEGG: ate:Athe_0208 protein of unknown function DUF1284.
       0.843
Your Current Organism:
Caldicellulosiruptor owensensis
NCBI taxonomy Id: 632518
Other names: C. owensensis OL, Caldicellulosiruptor owensensis DSM 13100, Caldicellulosiruptor owensensis OL, Caldicellulosiruptor owensensis str. OL, Caldicellulosiruptor owensensis strain OL
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