Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ADQ03757.1TIGRFAM: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase; KEGG: ate:Athe_0212 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase; PFAM: 78-dihydro-6-hydroxymethylpterin-pyrophosphokinase HPPK. (157 aa)    
Predicted Functional Partners:
ADQ03755.1
TIGRFAM: dihydropteroate synthase; KEGG: ate:Athe_0210 dihydropteroate synthase; PFAM: dihydropteroate synthase DHPS.
 
 0.999
ADQ03764.1
KEGG: ate:Athe_0219 hypothetical protein.
  
  
 0.906
folE2
GTP cyclohydrolase I; Converts GTP to 7,8-dihydroneopterin triphosphate.
   
 0.903
ADQ03942.1
KEGG: ate:Athe_0500 beta-lactamase domain protein.
     
  0.900
birA
biotin/acetyl-CoA-carboxylase ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family.
  
  
 0.872
ADQ04314.1
PFAM: protein of unknown function DUF523; KEGG: ate:Athe_0936 protein of unknown function DUF523.
 
      0.860
ADQ04827.1
KEGG: ate:Athe_1490 FolC bifunctional protein; TIGRFAM: FolC bifunctional protein; PFAM: cytoplasmic peptidoglycan synthetase domain protein; Mur ligase middle domain protein; Belongs to the folylpolyglutamate synthase family.
  
 0.834
ADQ03756.1
KEGG: ate:Athe_0211 hypothetical protein.
       0.779
ADQ03758.1
PFAM: short-chain dehydrogenase/reductase SDR; KEGG: ate:Athe_0213 short-chain dehydrogenase/reductase SDR.
       0.779
ADQ04268.1
TIGRFAM: phospho-2-dehydro-3-deoxyheptonate aldolase; KEGG: ate:Athe_0845 phospho-2-dehydro-3-deoxyheptonate aldolase; PFAM: DAHP synthetase I/KDSA.
    
 0.739
Your Current Organism:
Caldicellulosiruptor owensensis
NCBI taxonomy Id: 632518
Other names: C. owensensis OL, Caldicellulosiruptor owensensis DSM 13100, Caldicellulosiruptor owensensis OL, Caldicellulosiruptor owensensis str. OL, Caldicellulosiruptor owensensis strain OL
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