Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ADQ03763.1KEGG: ate:Athe_0218 stage II sporulation protein D; TIGRFAM: stage II sporulation protein D; SpoIID/LytB domain protein; PFAM: Stage II sporulation protein D. (345 aa)    
Predicted Functional Partners:
ADQ03762.1
Protein serine/threonine phosphatase; PFAM: Stage II sporulation protein E; KEGG: ate:Athe_0217 protein serine/threonine phosphatase; SMART: protein phosphatase 2C domain protein.
 
   
 0.928
ADQ05675.1
Stage IV sporulation protein A; ATPase. Has a role at an early stage in the morphogenesis of the spore coat.
  
  
 0.875
ADQ04105.1
KEGG: ate:Athe_0646 hypothetical protein.
 
   
 0.766
ADQ05222.1
PFAM: Sporulation stage II protein R; KEGG: ate:Athe_1953 hypothetical protein.
  
   
 0.746
ADQ05078.1
KEGG: ate:Athe_1789 stage II sporulation protein P; TIGRFAM: stage II sporulation protein P; PFAM: Stage II sporulation P family protein.
  
  
 0.700
spoIIAB
Putative anti-sigma regulatory factor, serine/threonine protein kinase; Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition.
  
   
 0.682
ADQ04344.1
SMART: AAA ATPase; KEGG: ate:Athe_0990 AAA ATPase.
  
  
 0.679
ADQ05731.1
KEGG: ate:Athe_2731 stage V sporulation protein AC; TIGRFAM: stage V sporulation protein AC; PFAM: SpoVA protein.
  
   
 0.670
ADQ05733.1
KEGG: ate:Athe_2733 stage V sporulation protein AE; TIGRFAM: stage V sporulation protein AE; PFAM: SpoVA protein.
  
   
 0.662
ADQ05732.1
KEGG: ate:Athe_2732 stage V sporulation protein AD; TIGRFAM: stage V sporulation protein AD; PFAM: Stage V sporulation AD family protein.
  
   
 0.655
Your Current Organism:
Caldicellulosiruptor owensensis
NCBI taxonomy Id: 632518
Other names: C. owensensis OL, Caldicellulosiruptor owensensis DSM 13100, Caldicellulosiruptor owensensis OL, Caldicellulosiruptor owensensis str. OL, Caldicellulosiruptor owensensis strain OL
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