Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
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Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ADQ03815.1HAD-superfamily hydrolase, subfamily IIA; Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro; Belongs to the HAD-like hydrolase superfamily. NagD family. (275 aa)    
Predicted Functional Partners:
ADQ03816.1
PFAM: protein of unknown function DUF159; KEGG: ate:Athe_0318 protein of unknown function DUF159; Belongs to the SOS response-associated peptidase family.
  
    0.784
ADQ03814.1
PFAM: glycosyl transferase group 1; KEGG: ate:Athe_0316 glycosyl transferase group 1.
       0.727
murB
UDP-N-acetylenolpyruvoylglucosamine reductase; Cell wall formation.
       0.613
ADQ04224.1
PFAM: 3-dehydroquinate synthase; KEGG: csc:Csac_0948 glutamate-1-semialdehyde 2,1-aminomutase.
 
  
 0.540
ADQ05264.1
KEGG: ate:Athe_2041 RNA polymerase, sigma-24 subunit, ECF subfamily; TIGRFAM: RNA polymerase sigma-H factor; RNA polymerase sigma factor, sigma-70 family; PFAM: sigma-70 region 2 domain protein; Sigma-70 region 4 type 2.
  
    0.511
ADQ03813.1
KEGG: ate:Athe_0315 transcriptional regulator, ArsR family; PFAM: regulatory protein ArsR; SMART: regulatory protein ArsR.
  
    0.478
ADQ03812.1
KEGG: ate:Athe_0314 heavy metal translocating P-type ATPase; TIGRFAM: heavy metal translocating P-type ATPase; cadmium-translocating P-type ATPase; ATPase, P-type (transporting), HAD superfamily, subfamily IC; PFAM: E1-E2 ATPase-associated domain protein; Heavy metal transport/detoxification protein; Haloacid dehalogenase domain protein hydrolase.
  
  
 0.463
metG
methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
   
   0.430
araB
L-ribulokinase; KEGG: ate:Athe_2229 L-ribulokinase; TIGRFAM: L-ribulokinase; PFAM: Carbohydrate kinase, FGGY-like.
 
  
 0.408
Your Current Organism:
Caldicellulosiruptor owensensis
NCBI taxonomy Id: 632518
Other names: C. owensensis OL, Caldicellulosiruptor owensensis DSM 13100, Caldicellulosiruptor owensensis OL, Caldicellulosiruptor owensensis str. OL, Caldicellulosiruptor owensensis strain OL
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