| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ADQ03830.1 | ADQ03831.1 | Calow_0225 | Calow_0226 | PFAM: short-chain dehydrogenase/reductase SDR; KEGG: cpy:Cphy_3619 short-chain dehydrogenase/reductase SDR; Belongs to the short-chain dehydrogenases/reductases (SDR) family. | PFAM: AMMECR1 domain protein; Extradiol ring-cleavage dioxygenase class III protein subunit B; KEGG: ate:Athe_0359 AMMECR1 domain protein. | 0.498 |
| ADQ03830.1 | ADQ03832.1 | Calow_0225 | Calow_0227 | PFAM: short-chain dehydrogenase/reductase SDR; KEGG: cpy:Cphy_3619 short-chain dehydrogenase/reductase SDR; Belongs to the short-chain dehydrogenases/reductases (SDR) family. | KEGG: ate:Athe_0360 radical SAM domain protein; PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB. | 0.490 |
| ADQ03830.1 | ADQ03834.1 | Calow_0225 | Calow_0229 | PFAM: short-chain dehydrogenase/reductase SDR; KEGG: cpy:Cphy_3619 short-chain dehydrogenase/reductase SDR; Belongs to the short-chain dehydrogenases/reductases (SDR) family. | PFAM: YbbR family protein; KEGG: ate:Athe_0362 YbbR family protein. | 0.441 |
| ADQ03830.1 | dacA | Calow_0225 | Calow_0228 | PFAM: short-chain dehydrogenase/reductase SDR; KEGG: cpy:Cphy_3619 short-chain dehydrogenase/reductase SDR; Belongs to the short-chain dehydrogenases/reductases (SDR) family. | Protein of unknown function DUF147; Catalyzes the condensation of 2 ATP molecules into cyclic di- AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria; Belongs to the adenylate cyclase family. DacA/CdaA subfamily. | 0.452 |
| ADQ03830.1 | uvrC | Calow_0225 | Calow_0230 | PFAM: short-chain dehydrogenase/reductase SDR; KEGG: cpy:Cphy_3619 short-chain dehydrogenase/reductase SDR; Belongs to the short-chain dehydrogenases/reductases (SDR) family. | Excinuclease ABC, C subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision. | 0.515 |
| ADQ03831.1 | ADQ03830.1 | Calow_0226 | Calow_0225 | PFAM: AMMECR1 domain protein; Extradiol ring-cleavage dioxygenase class III protein subunit B; KEGG: ate:Athe_0359 AMMECR1 domain protein. | PFAM: short-chain dehydrogenase/reductase SDR; KEGG: cpy:Cphy_3619 short-chain dehydrogenase/reductase SDR; Belongs to the short-chain dehydrogenases/reductases (SDR) family. | 0.498 |
| ADQ03831.1 | ADQ03832.1 | Calow_0226 | Calow_0227 | PFAM: AMMECR1 domain protein; Extradiol ring-cleavage dioxygenase class III protein subunit B; KEGG: ate:Athe_0359 AMMECR1 domain protein. | KEGG: ate:Athe_0360 radical SAM domain protein; PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB. | 0.955 |
| ADQ03831.1 | ADQ03834.1 | Calow_0226 | Calow_0229 | PFAM: AMMECR1 domain protein; Extradiol ring-cleavage dioxygenase class III protein subunit B; KEGG: ate:Athe_0359 AMMECR1 domain protein. | PFAM: YbbR family protein; KEGG: ate:Athe_0362 YbbR family protein. | 0.774 |
| ADQ03831.1 | ADQ04564.1 | Calow_0226 | Calow_1001 | PFAM: AMMECR1 domain protein; Extradiol ring-cleavage dioxygenase class III protein subunit B; KEGG: ate:Athe_0359 AMMECR1 domain protein. | PFAM: aldo/keto reductase; KEGG: ate:Athe_1210 aldo/keto reductase. | 0.409 |
| ADQ03831.1 | ADQ04943.1 | Calow_0226 | Calow_1392 | PFAM: AMMECR1 domain protein; Extradiol ring-cleavage dioxygenase class III protein subunit B; KEGG: ate:Athe_0359 AMMECR1 domain protein. | 2'-5' RNA ligase; Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester; Belongs to the 2H phosphoesterase superfamily. ThpR family. | 0.480 |
| ADQ03831.1 | dacA | Calow_0226 | Calow_0228 | PFAM: AMMECR1 domain protein; Extradiol ring-cleavage dioxygenase class III protein subunit B; KEGG: ate:Athe_0359 AMMECR1 domain protein. | Protein of unknown function DUF147; Catalyzes the condensation of 2 ATP molecules into cyclic di- AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria; Belongs to the adenylate cyclase family. DacA/CdaA subfamily. | 0.774 |
| ADQ03831.1 | hprK | Calow_0226 | Calow_0231 | PFAM: AMMECR1 domain protein; Extradiol ring-cleavage dioxygenase class III protein subunit B; KEGG: ate:Athe_0359 AMMECR1 domain protein. | HPr kinase; Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr). The two antagonistic activities of HprK/P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (gluc [...] | 0.510 |
| ADQ03831.1 | nnrE | Calow_0226 | Calow_1621 | PFAM: AMMECR1 domain protein; Extradiol ring-cleavage dioxygenase class III protein subunit B; KEGG: ate:Athe_0359 AMMECR1 domain protein. | Carbohydrate kinase, YjeF related protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow t [...] | 0.536 |
| ADQ03831.1 | uvrC | Calow_0226 | Calow_0230 | PFAM: AMMECR1 domain protein; Extradiol ring-cleavage dioxygenase class III protein subunit B; KEGG: ate:Athe_0359 AMMECR1 domain protein. | Excinuclease ABC, C subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision. | 0.586 |
| ADQ03832.1 | ADQ03830.1 | Calow_0227 | Calow_0225 | KEGG: ate:Athe_0360 radical SAM domain protein; PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB. | PFAM: short-chain dehydrogenase/reductase SDR; KEGG: cpy:Cphy_3619 short-chain dehydrogenase/reductase SDR; Belongs to the short-chain dehydrogenases/reductases (SDR) family. | 0.490 |
| ADQ03832.1 | ADQ03831.1 | Calow_0227 | Calow_0226 | KEGG: ate:Athe_0360 radical SAM domain protein; PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB. | PFAM: AMMECR1 domain protein; Extradiol ring-cleavage dioxygenase class III protein subunit B; KEGG: ate:Athe_0359 AMMECR1 domain protein. | 0.955 |
| ADQ03832.1 | ADQ03834.1 | Calow_0227 | Calow_0229 | KEGG: ate:Athe_0360 radical SAM domain protein; PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB. | PFAM: YbbR family protein; KEGG: ate:Athe_0362 YbbR family protein. | 0.727 |
| ADQ03832.1 | ADQ04943.1 | Calow_0227 | Calow_1392 | KEGG: ate:Athe_0360 radical SAM domain protein; PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB. | 2'-5' RNA ligase; Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester; Belongs to the 2H phosphoesterase superfamily. ThpR family. | 0.438 |
| ADQ03832.1 | dacA | Calow_0227 | Calow_0228 | KEGG: ate:Athe_0360 radical SAM domain protein; PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB. | Protein of unknown function DUF147; Catalyzes the condensation of 2 ATP molecules into cyclic di- AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria; Belongs to the adenylate cyclase family. DacA/CdaA subfamily. | 0.730 |
| ADQ03832.1 | hprK | Calow_0227 | Calow_0231 | KEGG: ate:Athe_0360 radical SAM domain protein; PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB. | HPr kinase; Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr). The two antagonistic activities of HprK/P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (gluc [...] | 0.508 |
