Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ADQ03834.1PFAM: YbbR family protein; KEGG: ate:Athe_0362 YbbR family protein. (412 aa)    
Predicted Functional Partners:
dacA
Protein of unknown function DUF147; Catalyzes the condensation of 2 ATP molecules into cyclic di- AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria; Belongs to the adenylate cyclase family. DacA/CdaA subfamily.
 
  
 0.962
ADQ03831.1
PFAM: AMMECR1 domain protein; Extradiol ring-cleavage dioxygenase class III protein subunit B; KEGG: ate:Athe_0359 AMMECR1 domain protein.
       0.774
ADQ03832.1
KEGG: ate:Athe_0360 radical SAM domain protein; PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB.
       0.727
uvrC
Excinuclease ABC, C subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.
     
 0.692
hprK
HPr kinase; Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr). The two antagonistic activities of HprK/P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (gluc [...]
       0.589
ADQ05582.1
PFAM: S-layer domain-containing protein; KEGG: ate:Athe_2342 S-layer domain protein.
  
     0.575
ADQ04160.1
KEGG: ate:Athe_0715 hypothetical protein.
  
     0.528
ADQ05269.1
TIGRFAM: primosome, DnaD subunit; KEGG: ate:Athe_2045 primosome, DnaD subunit.
 
     0.527
ADQ05270.1
SMART: AAA ATPase; KEGG: ate:Athe_2046 AAA ATPase.
 
     0.498
ADQ04571.1
PFAM: NUDIX hydrolase; KEGG: ate:Athe_1217 NUDIX hydrolase.
 
     0.479
Your Current Organism:
Caldicellulosiruptor owensensis
NCBI taxonomy Id: 632518
Other names: C. owensensis OL, Caldicellulosiruptor owensensis DSM 13100, Caldicellulosiruptor owensensis OL, Caldicellulosiruptor owensensis str. OL, Caldicellulosiruptor owensensis strain OL
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