Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ADQ03860.1PFAM: metalloenzyme domain protein; KEGG: ate:Athe_0425 metalloenzyme domain protein. (293 aa)    
Predicted Functional Partners:
tpiA
Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family.
  
 0.996
eno
Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.
  
 0.968
ADQ05291.1
TIGRFAM: glycerate kinase; KEGG: ate:Athe_2071 glycerate kinase; PFAM: glycerate kinase; Belongs to the glycerate kinase type-1 family.
  
  
 0.917
gpmI
Phosphoglycerate mutase, 2,3-bisphosphoglycerate-independent; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate.
  
  
 
0.905
ADQ05344.1
KEGG: ate:Athe_2125 D-3-phosphoglycerate dehydrogenase; TIGRFAM: D-3-phosphoglycerate dehydrogenase; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; D-isomer specific 2-hydroxyacid dehydrogenase catalytic region; amino acid-binding ACT domain protein.
  
 
 0.905
ADQ04078.1
TIGRFAM: bifunctional phosphoglucose/phosphomannose isomerase; KEGG: ate:Athe_0619 bifunctional phosphoglucose/phosphomannose isomerase; PFAM: Bifunctional glucose-6-phosphate/mannose-6-phosphate isomerase-like; sugar isomerase (SIS).
  
 
 0.859
ADQ04080.1
TIGRFAM: fructose-1,6-bisphosphate aldolase, class II; ketose-bisphosphate aldolase; KEGG: ate:Athe_0621 fructose-1,6-bisphosphate aldolase, class II; PFAM: ketose-bisphosphate aldolase class-II.
   
 
 0.842
ADQ05633.1
TIGRFAM: ketose-bisphosphate aldolase; KEGG: ate:Athe_2390 ketose-bisphosphate aldolase; PFAM: ketose-bisphosphate aldolase class-II.
   
 
 0.842
ADQ03859.1
Protein of unknown function DUF710; Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division.
 
     0.827
ADQ04745.1
TIGRFAM: pyruvate, phosphate dikinase; KEGG: ate:Athe_1409 pyruvate, phosphate dikinase; PFAM: pyruvate phosphate dikinase PEP/pyruvate-binding; PEP-utilising protein mobile region; PEP-utilizing protein; Belongs to the PEP-utilizing enzyme family.
    
 0.827
Your Current Organism:
Caldicellulosiruptor owensensis
NCBI taxonomy Id: 632518
Other names: C. owensensis OL, Caldicellulosiruptor owensensis DSM 13100, Caldicellulosiruptor owensensis OL, Caldicellulosiruptor owensensis str. OL, Caldicellulosiruptor owensensis strain OL
Server load: low (14%) [HD]