Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ADQ03870.1KEGG: ate:Athe_0435 anti-sigma-factor antagonist; TIGRFAM: anti-anti-sigma factor; PFAM: Sulfate transporter/antisigma-factor antagonist STAS. (102 aa)    
Predicted Functional Partners:
ADQ03871.1
KEGG: ate:Athe_0436 putative anti-sigma regulatory factor, serine/threonine protein kinase.
 
 
 0.998
ADQ05749.1
TIGRFAM: PAS sensor protein; PFAM: Stage II sporulation protein E; PAS fold-4 domain protein; KEGG: ate:Athe_2749 putative PAS/PAC sensor protein; SMART: protein phosphatase 2C domain protein.
 
 
 0.923
ADQ03872.1
KEGG: ate:Athe_0437 RNA polymerase, sigma 28 subunit, Sig B/F/G subfamily; TIGRFAM: RNA polymerase sigma-70 factor, sigma-B/F/G subfamily; RNA polymerase sigma factor, sigma-70 family; PFAM: sigma-70 region 3 domain protein; sigma-70 region 2 domain protein; sigma-70 region 4 domain protein.
 
 
 0.916
ADQ05379.1
KEGG: ate:Athe_2160 CheC, inhibitor of MCP methylation / FliN fusion protein; TIGRFAM: flagellar motor switch protein FliN; PFAM: surface presentation of antigens (SPOA) protein; CheC domain protein.
  
   0.879
ADQ05637.1
PFAM: ATP-binding region ATPase domain protein; KEGG: ate:Athe_2394 putative anti-sigma regulatory factor, serine/threonine protein kinase.
 
 
 0.843
ADQ04006.1
KEGG: tte:TTE1049 anti-sigma regulatory factor (Ser/Thr protein kinase); PFAM: ATP-binding region ATPase domain protein; SMART: ATP-binding region ATPase domain protein.
  
 
 0.781
ADQ04645.1
PFAM: ATP-binding region ATPase domain protein; KEGG: ate:Athe_1291 putative anti-sigma regulatory factor, serine/threonine protein kinase.
  
 
 0.781
spoIIAB
Putative anti-sigma regulatory factor, serine/threonine protein kinase; Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition.
  
 
 0.772
ADQ05576.1
PFAM: Flagellar protein FlgJ-like; KEGG: ate:Athe_2336 hypothetical protein.
  
    0.722
ADQ04007.1
KEGG: tte:TTE1051 hypothetical protein; PFAM: ATP-binding region ATPase domain protein; SMART: protein phosphatase 2C domain protein.
  
 
 0.708
Your Current Organism:
Caldicellulosiruptor owensensis
NCBI taxonomy Id: 632518
Other names: C. owensensis OL, Caldicellulosiruptor owensensis DSM 13100, Caldicellulosiruptor owensensis OL, Caldicellulosiruptor owensensis str. OL, Caldicellulosiruptor owensensis strain OL
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.