Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ADQ03884.1PFAM: protein of unknown function DUF58; KEGG: ate:Athe_0449 protein of unknown function DUF58. (382 aa)    
Predicted Functional Partners:
ADQ05654.1
PFAM: ATPase associated with various cellular activities AAA_3; KEGG: ate:Athe_2560 ATPase associated with various cellular activities AAA_3.
 
  
 0.818
ADQ03826.1
PFAM: major facilitator superfamily MFS_1; KEGG: ate:Athe_0342 major facilitator superfamily MFS_1.
 
     0.613
nnrE
Carbohydrate kinase, YjeF related protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow t [...]
     
 0.531
ADQ05652.1
KEGG: csc:Csac_0293 hypothetical protein.
  
     0.515
ADQ04600.1
KEGG: ate:Athe_1246 hypothetical protein.
  
     0.505
ADQ03885.1
KEGG: ate:Athe_2764 protein of unknown function UPF0236.
       0.493
ADQ04222.1
KEGG: ate:Athe_0800 tetratricopeptide TPR_2 repeat protein; PFAM: Tetratricopeptide TPR_1 repeat-containing protein; Tetratricopeptide TPR_3 repeat-containing protein; SMART: Tetratricopeptide repeat.
 
  
 0.471
ADQ04571.1
PFAM: NUDIX hydrolase; KEGG: ate:Athe_1217 NUDIX hydrolase.
 
     0.443
ADQ04901.1
KEGG: csc:Csac_0666 hypothetical protein.
  
     0.435
ADQ05639.1
KEGG: ate:Athe_2396 hypothetical protein.
  
  
 0.427
Your Current Organism:
Caldicellulosiruptor owensensis
NCBI taxonomy Id: 632518
Other names: C. owensensis OL, Caldicellulosiruptor owensensis DSM 13100, Caldicellulosiruptor owensensis OL, Caldicellulosiruptor owensensis str. OL, Caldicellulosiruptor owensensis strain OL
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