Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Score
ADQ03891.1RNA methyltransferase, TrmA family; KEGG: csc:Csac_0465 RNA methyltransferase; TIGRFAM: RNA methyltransferase, TrmA family; PFAM: deoxyribonuclease/rho motif-related TRAM; (Uracil-5)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. (451 aa)    
Predicted Functional Partners:
ADQ03892.1
PFAM: protein of unknown function DUF1232; KEGG: ate:Athe_0456 protein of unknown function DUF1232.
       0.743
ADQ03893.1
methylated-DNA/protein-cysteine methyltransferase; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
       0.706
ADQ03889.1
KEGG: ate:Athe_0453 hemerythrin-like metal-binding protein; TIGRFAM: hemerythrin-like metal-binding protein; PFAM: Hemerythrin HHE cation binding domain protein.
       0.595
ADQ03890.1
KEGG: mpu:MYPU_6300 signal peptidase I (SPase I) (leader peptidase I).
       0.594
ADQ04654.1
Maf protein; Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.
      0.592
ADQ05508.1
tRNA (adenine-N(1)-)-methyltransferase; Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA.
   
  
 0.559
guaA
GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP.
  
  
 0.556
ADQ03887.1
KEGG: ate:Athe_0451 hypothetical protein.
  
    0.554
pheT
KEGG: ate:Athe_1284 phenylalanyl-tRNA synthetase, beta subunit; TIGRFAM: phenylalanyl-tRNA synthetase, beta subunit.
 
  
 0.528
murB
UDP-N-acetylenolpyruvoylglucosamine reductase; Cell wall formation.
  
  
 0.515
Your Current Organism:
Caldicellulosiruptor owensensis
NCBI taxonomy Id: 632518
Other names: C. owensensis OL, Caldicellulosiruptor owensensis DSM 13100, Caldicellulosiruptor owensensis OL, Caldicellulosiruptor owensensis str. OL, Caldicellulosiruptor owensensis strain OL
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