Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
rbsKRibokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway. (312 aa)    
Predicted Functional Partners:
rbsD
RbsD or FucU transport; Catalyzes the interconversion of beta-pyran and beta-furan forms of D-ribose.
 
 
 0.997
deoC
Deoxyribose-phosphate aldolase; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate; Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
   
 0.970
ADQ04091.1
TIGRFAM: sugar-phosphate isomerase, RpiB/LacA/LacB family; ribose 5-phosphate isomerase B; KEGG: ate:Athe_0632 sugar-phosphate isomerase, RpiB/LacA/LacB family; PFAM: Ribose/galactose isomerase.
    
 0.929
prs
Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
  
 0.924
ADQ03914.1
PFAM: inner-membrane translocator; KEGG: smd:Smed_3767 monosaccharide-transporting ATPase; Belongs to the binding-protein-dependent transport system permease family.
 
  
 0.923
ADQ05568.1
PFAM: Transketolase domain-containing protein; Transketolase central region; KEGG: ate:Athe_2328 transketolase domain protein.
  
 0.917
ADQ03917.1
PFAM: Transketolase domain-containing protein; KEGG: tna:CTN_1622 transketolase, N-terminal subunit.
    
 0.905
ADQ05280.1
PFAM: Transketolase domain-containing protein; KEGG: ate:Athe_2060 transketolase domain protein.
    
 0.905
ADQ03918.1
PFAM: Transketolase central region; Transketolase domain-containing protein; KEGG: tna:CTN_1623 transketolase, C-terminal subunit.
    
  0.903
ADQ05279.1
PFAM: Transketolase central region; Transketolase domain-containing protein; KEGG: csc:Csac_1352 transketolase, central region.
    
  0.903
Your Current Organism:
Caldicellulosiruptor owensensis
NCBI taxonomy Id: 632518
Other names: C. owensensis OL, Caldicellulosiruptor owensensis DSM 13100, Caldicellulosiruptor owensensis OL, Caldicellulosiruptor owensensis str. OL, Caldicellulosiruptor owensensis strain OL
Server load: low (36%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.