Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ADQ03923.1PFAM: aldo/keto reductase; KEGG: ate:Athe_0465 aldo/keto reductase. (340 aa)    
Predicted Functional Partners:
ADQ03924.1
KEGG: csc:Csac_1116 ABC transporter related; PFAM: ABC transporter related; ABC transporter transmembrane region; SMART: AAA ATPase.
       0.779
ADQ03925.1
CRISPR-associated protein Cas6; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).
       0.722
ADQ03927.1
PFAM: GCN5-related N-acetyltransferase; KEGG: csc:Csac_1119 GCN5-related N-acetyltransferase.
 
     0.493
ADQ03926.1
Alpha-galactosidase; KEGG: ate:Athe_0468 glycoside hydrolase clan GH-D; PFAM: glycoside hydrolase clan GH-D.
       0.459
ADQ05435.1
KEGG: ate:Athe_2219 4Fe-4S ferredoxin iron-sulfur binding domain protein.
 
    0.445
ADQ05155.1
KEGG: ate:Athe_1893 protein of unknown function DUF1121.
   
   0.435
ADQ05625.1
KEGG: ate:Athe_2382 protein of unknown function DUF1121.
   
   0.435
ADQ03933.1
PFAM: Rubrerythrin; KEGG: ate:Athe_0477 rubrerythrin.
    
   0.402
ADQ05236.1
KEGG: ate:Athe_1977 hypothetical protein.
    
   0.402
ADQ05354.1
KEGG: ate:Athe_2135 protein of unknown function DUF362.
 
    0.402
Your Current Organism:
Caldicellulosiruptor owensensis
NCBI taxonomy Id: 632518
Other names: C. owensensis OL, Caldicellulosiruptor owensensis DSM 13100, Caldicellulosiruptor owensensis OL, Caldicellulosiruptor owensensis str. OL, Caldicellulosiruptor owensensis strain OL
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