Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ADQ03931.1PFAM: fumarate lyase; Fumarase C-like; KEGG: ate:Athe_0474 fumarate lyase. (461 aa)    
Predicted Functional Partners:
ADQ04567.1
L-aspartate oxidase; Catalyzes the oxidation of L-aspartate to iminoaspartate.
 
   
 0.983
ADQ04510.1
KEGG: ate:Athe_1129 adenylosuccinate lyase; TIGRFAM: adenylosuccinate lyase; PFAM: Adenylosuccinate lyase-like; fumarate lyase.
     
 0.907
argH
KEGG: ate:Athe_1248 argininosuccinate lyase; TIGRFAM: argininosuccinate lyase; PFAM: fumarate lyase.
     
0.907
ADQ04509.1
PFAM: aminotransferase class I and II; KEGG: ate:Athe_1128 aminotransferase class I and II.
    
 0.905
purA
Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.
     
 0.904
ADQ04874.1
PFAM: asparagine synthase; glutamine amidotransferase class-II; manually curated; KEGG: ate:Athe_1539 asparagine synthase (glutamine-hydrolyzing); TIGRFAM: asparagine synthase (glutamine-hydrolyzing).
     
 0.904
pyrB
TIGRFAM: aspartate carbamoyltransferase; KEGG: ate:Athe_1375 aspartate carbamoyltransferase; PFAM: aspartate/ornithine carbamoyltransferase carbamoyl-P binding domain; aspartate/ornithine carbamoyltransferase Asp/Orn-binding region; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
     
  0.900
ADQ03930.1
KEGG: csc:Csac_1123 small GTP-binding protein; TIGRFAM: small GTP-binding protein; PFAM: GTP-binding protein HSR1-related.
 
  
 0.825
argG
TIGRFAM: argininosuccinate synthase; KEGG: ate:Athe_1249 argininosuccinate synthase; PFAM: argininosuccinate synthase; Belongs to the argininosuccinate synthase family. Type 1 subfamily.
     
 0.821
ADQ04483.1
PFAM: Pyruvate/ketoisovalerate oxidoreductase, catalytic domain; KEGG: ate:Athe_1098 pyruvate ferredoxin/flavodoxin oxidoreductase.
    
 0.817
Your Current Organism:
Caldicellulosiruptor owensensis
NCBI taxonomy Id: 632518
Other names: C. owensensis OL, Caldicellulosiruptor owensensis DSM 13100, Caldicellulosiruptor owensensis OL, Caldicellulosiruptor owensensis str. OL, Caldicellulosiruptor owensensis strain OL
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