Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
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Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ADQ03943.1PFAM: short-chain dehydrogenase/reductase SDR; KEGG: ate:Athe_0501 short-chain dehydrogenase/reductase SDR; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (267 aa)    
Predicted Functional Partners:
ADQ04211.1
PFAM: AMP-dependent synthetase and ligase; KEGG: ate:Athe_0789 AMP-dependent synthetase and ligase.
  
 
 0.677
ADQ03942.1
KEGG: ate:Athe_0500 beta-lactamase domain protein.
       0.575
ADQ03941.1
PFAM: amidohydrolase 2; KEGG: ate:Athe_0499 amidohydrolase 2.
 
     0.526
ADQ03776.1
PFAM: Nucleotidyl transferase; transferase hexapeptide repeat containing protein; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I; KEGG: ate:Athe_0233 nucleotidyl transferase.
   
   0.489
ADQ05602.1
PFAM: sodium/calcium exchanger membrane region; KEGG: ate:Athe_2364 sodium/calcium exchanger membrane region.
    
   0.484
secY
Preprotein translocase, SecY subunit; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.
   
   0.463
ADQ03944.1
KEGG: ate:Athe_0502 acetolactate synthase, large subunit, biosynthetic type; TIGRFAM: acetolactate synthase, large subunit, biosynthetic type; PFAM: thiamine pyrophosphate TPP-binding domain-containing protein; thiamine pyrophosphate central domain-containing protein.
     
 0.457
ADQ03758.1
PFAM: short-chain dehydrogenase/reductase SDR; KEGG: ate:Athe_0213 short-chain dehydrogenase/reductase SDR.
 
 
0.438
ADQ04535.1
3-oxoacyl-(acyl-carrier-protein) reductase; Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis. Belongs to the short-chain dehydrogenases/reductases (SDR) family.
 
 
0.435
ADQ04139.1
PFAM: short-chain dehydrogenase/reductase SDR; KEGG: ate:Athe_0698 short-chain dehydrogenase/reductase SDR.
 
 
0.431
Your Current Organism:
Caldicellulosiruptor owensensis
NCBI taxonomy Id: 632518
Other names: C. owensensis OL, Caldicellulosiruptor owensensis DSM 13100, Caldicellulosiruptor owensensis OL, Caldicellulosiruptor owensensis str. OL, Caldicellulosiruptor owensensis strain OL
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