Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ADQ04002.1KEGG: ate:Athe_2764 protein of unknown function UPF0236. (479 aa)    
Predicted Functional Partners:
ADQ04145.1
PFAM: Transketolase central region; dehydrogenase E1 component; Transketolase domain-containing protein; KEGG: ate:Athe_0704 transketolase central region.
  
  0.833
ADQ04429.1
KEGG: ate:Athe_1045 serine/threonine protein kinase with PASTA sensor(s); PFAM: Serine/threonine-protein kinase-like domain; PASTA domain containing protein; SMART: serine/threonine protein kinase; Tyrosine-protein kinase, catalytic domain; PASTA domain containing protein.
  
 
 0.701
ADQ04426.1
Sun protein; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.
  
   0.547
ADQ04001.1
TIGRFAM: metal dependent phophohydrolase; PFAM: metal-dependent phosphohydrolase HD sub domain; KEGG: tme:Tmel_0998 metal dependent phosphohydrolase; SMART: metal-dependent phosphohydrolase HD region.
       0.492
ADQ04415.1
PFAM: histone deacetylase superfamily; KEGG: ate:Athe_1031 histone deacetylase superfamily.
   
   0.492
ADQ04966.1
TIGRFAM: Flagellar operon protein YvyF; KEGG: ate:Athe_1678 hypothetical protein.
   
   0.489
ADQ04222.1
KEGG: ate:Athe_0800 tetratricopeptide TPR_2 repeat protein; PFAM: Tetratricopeptide TPR_1 repeat-containing protein; Tetratricopeptide TPR_3 repeat-containing protein; SMART: Tetratricopeptide repeat.
    
   0.483
ADQ04003.1
TIGRFAM: metal dependent phophohydrolase; PFAM: metal-dependent phosphohydrolase HD sub domain; KEGG: nth:Nther_2138 metal dependent phosphohydrolase; SMART: metal-dependent phosphohydrolase HD region.
  
    0.470
ADQ04756.1
KEGG: ate:Athe_1420 heat shock protein DnaJ domain protein; PFAM: heat shock protein DnaJ domain protein; SMART: heat shock protein DnaJ domain protein.
  
   0.454
dnaJ
Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...]
  
   0.454
Your Current Organism:
Caldicellulosiruptor owensensis
NCBI taxonomy Id: 632518
Other names: C. owensensis OL, Caldicellulosiruptor owensensis DSM 13100, Caldicellulosiruptor owensensis OL, Caldicellulosiruptor owensensis str. OL, Caldicellulosiruptor owensensis strain OL
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