Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ADQ04018.1PFAM: peptidase C26; KEGG: ate:Athe_0570 peptidase C26. (240 aa)    
Predicted Functional Partners:
ADQ04019.1
PFAM: MscS Mechanosensitive ion channel; KEGG: ate:Athe_0571 MscS mechanosensitive ion channel.
       0.796
ADQ04017.1
PFAM: ANTAR domain protein; KEGG: ate:Athe_0569 response regulator receiver and ANTAR domain protein.
       0.782
proS
prolyl-tRNA synthetase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves dea [...]
       0.652
ADQ04508.1
KEGG: ate:Athe_1127 membrane dipeptidase; PFAM: peptidase M19 renal dipeptidase.
      0.607
ADQ04102.1
TIGRFAM: glutamine synthetase, type I; KEGG: ate:Athe_0643 glutamine synthetase, type I; PFAM: glutamine synthetase catalytic region; glutamine synthetase beta-Grasp.
  
  
 0.600
ADQ04016.1
TIGRFAM: metal dependent phophohydrolase; PFAM: metal-dependent phosphohydrolase HD sub domain; KEGG: ate:Athe_0568 metal dependent phosphohydrolase; SMART: metal-dependent phosphohydrolase HD region.
       0.588
ADQ04021.1
Arylformamidase; KEGG: ate:Athe_0573 cyclase family protein; PFAM: cyclase family protein.
       0.458
ADQ04022.1
Helix-turn-helix domain protein; KEGG: tex:Teth514_0702 XRE family transcriptional regulator; PFAM: helix-turn-helix domain protein; SMART: helix-turn-helix domain protein.
  
  
 0.446
Your Current Organism:
Caldicellulosiruptor owensensis
NCBI taxonomy Id: 632518
Other names: C. owensensis OL, Caldicellulosiruptor owensensis DSM 13100, Caldicellulosiruptor owensensis OL, Caldicellulosiruptor owensensis str. OL, Caldicellulosiruptor owensensis strain OL
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