Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ADQ04019.1PFAM: MscS Mechanosensitive ion channel; KEGG: ate:Athe_0571 MscS mechanosensitive ion channel. (262 aa)    
Predicted Functional Partners:
ADQ04018.1
PFAM: peptidase C26; KEGG: ate:Athe_0570 peptidase C26.
       0.796
ADQ04017.1
PFAM: ANTAR domain protein; KEGG: ate:Athe_0569 response regulator receiver and ANTAR domain protein.
       0.780
proS
prolyl-tRNA synthetase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves dea [...]
       0.662
ADQ04016.1
TIGRFAM: metal dependent phophohydrolase; PFAM: metal-dependent phosphohydrolase HD sub domain; KEGG: ate:Athe_0568 metal dependent phosphohydrolase; SMART: metal-dependent phosphohydrolase HD region.
       0.588
ADQ04010.1
PFAM: GTP cyclohydrolase II; 34-dihydroxy-2-butanone 4-phosphate synthase; KEGG: ate:Athe_0562 3,4-dihydroxy-2-butanone 4-phosphate synthase; In the N-terminal section; belongs to the DHBP synthase family.
  
  
 0.509
ADQ04021.1
Arylformamidase; KEGG: ate:Athe_0573 cyclase family protein; PFAM: cyclase family protein.
       0.461
Your Current Organism:
Caldicellulosiruptor owensensis
NCBI taxonomy Id: 632518
Other names: C. owensensis OL, Caldicellulosiruptor owensensis DSM 13100, Caldicellulosiruptor owensensis OL, Caldicellulosiruptor owensensis str. OL, Caldicellulosiruptor owensensis strain OL
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