Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ADQ04021.1Arylformamidase; KEGG: ate:Athe_0573 cyclase family protein; PFAM: cyclase family protein. (209 aa)    
Predicted Functional Partners:
pckG
Phosphoenolpyruvate carboxykinase (GTP); Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle; Belongs to the phosphoenolpyruvate carboxykinase [GTP] family.
     
 0.805
ADQ04447.1
PFAM: malic protein NAD-binding; malic protein domain protein; KEGG: ate:Athe_1062 malate dehydrogenase (oxaloacetate-decarboxylating) (NADP(+)).
   
 
  0.801
ADQ05746.1
TIGRFAM: hydro-lyase, Fe-S type, tartrate/fumarate subfamily, alpha subunit; KEGG: ate:Athe_2746 hydro-lyase, Fe-S type, tartrate/fumarate subfamily, alpha subunit; PFAM: Fe-S type hydro-lyase tartrate/fumarate alpha region.
    
  0.801
ADQ03953.1
KEGG: ate:Athe_0510 hydro-lyase, Fe-S type, tartrate/fumarate subfamily, beta subunit; TIGRFAM: hydro-lyase, Fe-S type, tartrate/fumarate subfamily, beta subunit; PFAM: Fe-S type hydro-lyase tartrate/fumarate beta region.
     
  0.800
ADQ04673.1
PFAM: Conserved carboxylase region; pyruvate carboxyltransferase; KEGG: ate:Athe_1319 conserved carboxylase region.
     
  0.800
ADQ05518.1
Sodium ion-translocating decarboxylase, beta subunit; Tunnel subunit of the primary sodium pump glutaconyl-CoA decarboxylase (GCD).
     
  0.800
ADQ05520.1
PFAM: sodium pump decarboxylase gamma subunit; KEGG: csc:Csac_2484 sodium pump decarboxylase, gamma subunit.
     
  0.800
ADQ05521.1
PFAM: Conserved carboxylase region; pyruvate carboxyltransferase; KEGG: csc:Csac_2485 hypothetical protein.
     
  0.800
ADQ04022.1
Helix-turn-helix domain protein; KEGG: tex:Teth514_0702 XRE family transcriptional regulator; PFAM: helix-turn-helix domain protein; SMART: helix-turn-helix domain protein.
       0.550
proS
prolyl-tRNA synthetase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves dea [...]
       0.536
Your Current Organism:
Caldicellulosiruptor owensensis
NCBI taxonomy Id: 632518
Other names: C. owensensis OL, Caldicellulosiruptor owensensis DSM 13100, Caldicellulosiruptor owensensis OL, Caldicellulosiruptor owensensis str. OL, Caldicellulosiruptor owensensis strain OL
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.