Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ADQ04081.1KEGG: ate:Athe_0622 hypothetical protein. (47 aa)    
Predicted Functional Partners:
ADQ04082.1
PFAM: Radical SAM domain protein; KEGG: ate:Athe_0623 radical SAM domain protein.
 
 
   0.981
ADQ04083.1
KEGG: ate:Athe_0624 carbonic anhydrase.
       0.612
ADQ04868.1
PFAM: Domain of unknown function DUF1858; KEGG: ate:Athe_1535 domain of unknown function DUF1858.
  
     0.491
secD
Protein-export membrane protein SecD; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.
       0.478
secF
Protein-export membrane protein SecF; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.
       0.478
ADQ04080.1
TIGRFAM: fructose-1,6-bisphosphate aldolase, class II; ketose-bisphosphate aldolase; KEGG: ate:Athe_0621 fructose-1,6-bisphosphate aldolase, class II; PFAM: ketose-bisphosphate aldolase class-II.
       0.465
ADQ03954.1
PFAM: Orn/Lys/Arg decarboxylase major region; Orn/Lys/Arg decarboxylase domain protein; KEGG: ate:Athe_0511 Orn/Lys/Arg decarboxylase major region.
 
     0.446
ADQ05216.1
Radical SAM domain protein; KEGG: ate:Athe_1948 coproporphyrinogen dehydrogenase; PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB.
 
     0.445
ADQ04079.1
KEGG: ate:Athe_0620 PHP domain protein; PFAM: PHP domain protein; SMART: phosphoesterase PHP domain protein.
       0.433
ADQ04078.1
TIGRFAM: bifunctional phosphoglucose/phosphomannose isomerase; KEGG: ate:Athe_0619 bifunctional phosphoglucose/phosphomannose isomerase; PFAM: Bifunctional glucose-6-phosphate/mannose-6-phosphate isomerase-like; sugar isomerase (SIS).
 
     0.425
Your Current Organism:
Caldicellulosiruptor owensensis
NCBI taxonomy Id: 632518
Other names: C. owensensis OL, Caldicellulosiruptor owensensis DSM 13100, Caldicellulosiruptor owensensis OL, Caldicellulosiruptor owensensis str. OL, Caldicellulosiruptor owensensis strain OL
Server load: low (6%) [HD]