| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ADQ03822.1 | ADQ04113.1 | Calow_0217 | Calow_0531 | PFAM: homocysteine S-methyltransferase; methylenetetrahydrofolate reductase; KEGG: ate:Athe_0325 homocysteine S-methyltransferase. | TIGRFAM: threonine synthase; KEGG: ate:Athe_0655 threonine synthase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit. | 0.635 |
| ADQ03822.1 | ADQ04512.1 | Calow_0217 | Calow_0946 | PFAM: homocysteine S-methyltransferase; methylenetetrahydrofolate reductase; KEGG: ate:Athe_0325 homocysteine S-methyltransferase. | PFAM: amino acid-binding ACT domain protein; KEGG: ate:Athe_1132 amino acid-binding ACT domain protein. | 0.767 |
| ADQ03822.1 | ADQ05228.1 | Calow_0217 | Calow_1683 | PFAM: homocysteine S-methyltransferase; methylenetetrahydrofolate reductase; KEGG: ate:Athe_0325 homocysteine S-methyltransferase. | PFAM: homoserine dehydrogenase; homoserine dehydrogenase NAD-binding; KEGG: ate:Athe_1959 homoserine dehydrogenase. | 0.969 |
| ADQ03822.1 | ADQ05230.1 | Calow_0217 | Calow_1685 | PFAM: homocysteine S-methyltransferase; methylenetetrahydrofolate reductase; KEGG: ate:Athe_0325 homocysteine S-methyltransferase. | KEGG: ate:Athe_1961 aspartate kinase; TIGRFAM: aspartate kinase; aspartate kinase, monofunctional class; PFAM: aspartate/glutamate/uridylate kinase; amino acid-binding ACT domain protein; Belongs to the aspartokinase family. | 0.767 |
| ADQ03822.1 | guaB | Calow_0217 | Calow_1383 | PFAM: homocysteine S-methyltransferase; methylenetetrahydrofolate reductase; KEGG: ate:Athe_0325 homocysteine S-methyltransferase. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.564 |
| ADQ03822.1 | hisI | Calow_0217 | Calow_1251 | PFAM: homocysteine S-methyltransferase; methylenetetrahydrofolate reductase; KEGG: ate:Athe_0325 homocysteine S-methyltransferase. | KEGG: ate:Athe_1472 phosphoribosyl-ATP diphosphatase; TIGRFAM: phosphoribosyl-ATP diphosphatase; PFAM: phosphoribosyl-AMP cyclohydrolase; Phosphoribosyl-ATP pyrophosphohydrolase-like; In the N-terminal section; belongs to the PRA-CH family. | 0.622 |
| ADQ03822.1 | thrB | Calow_0217 | Calow_1684 | PFAM: homocysteine S-methyltransferase; methylenetetrahydrofolate reductase; KEGG: ate:Athe_0325 homocysteine S-methyltransferase. | Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. | 0.909 |
| ADQ04113.1 | ADQ03822.1 | Calow_0531 | Calow_0217 | TIGRFAM: threonine synthase; KEGG: ate:Athe_0655 threonine synthase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit. | PFAM: homocysteine S-methyltransferase; methylenetetrahydrofolate reductase; KEGG: ate:Athe_0325 homocysteine S-methyltransferase. | 0.635 |
| ADQ04113.1 | ADQ04512.1 | Calow_0531 | Calow_0946 | TIGRFAM: threonine synthase; KEGG: ate:Athe_0655 threonine synthase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit. | PFAM: amino acid-binding ACT domain protein; KEGG: ate:Athe_1132 amino acid-binding ACT domain protein. | 0.710 |
| ADQ04113.1 | ADQ05228.1 | Calow_0531 | Calow_1683 | TIGRFAM: threonine synthase; KEGG: ate:Athe_0655 threonine synthase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit. | PFAM: homoserine dehydrogenase; homoserine dehydrogenase NAD-binding; KEGG: ate:Athe_1959 homoserine dehydrogenase. | 0.963 |
| ADQ04113.1 | ADQ05230.1 | Calow_0531 | Calow_1685 | TIGRFAM: threonine synthase; KEGG: ate:Athe_0655 threonine synthase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit. | KEGG: ate:Athe_1961 aspartate kinase; TIGRFAM: aspartate kinase; aspartate kinase, monofunctional class; PFAM: aspartate/glutamate/uridylate kinase; amino acid-binding ACT domain protein; Belongs to the aspartokinase family. | 0.710 |
| ADQ04113.1 | cinA | Calow_0531 | Calow_0769 | TIGRFAM: threonine synthase; KEGG: ate:Athe_0655 threonine synthase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit. | KEGG: ate:Athe_0985 competence/damage-inducible protein CinA; TIGRFAM: competence/damage-inducible protein CinA; PFAM: CinA domain protein; molybdopterin binding domain; Belongs to the CinA family. | 0.609 |
| ADQ04113.1 | guaB | Calow_0531 | Calow_1383 | TIGRFAM: threonine synthase; KEGG: ate:Athe_0655 threonine synthase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.631 |
| ADQ04113.1 | hisI | Calow_0531 | Calow_1251 | TIGRFAM: threonine synthase; KEGG: ate:Athe_0655 threonine synthase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit. | KEGG: ate:Athe_1472 phosphoribosyl-ATP diphosphatase; TIGRFAM: phosphoribosyl-ATP diphosphatase; PFAM: phosphoribosyl-AMP cyclohydrolase; Phosphoribosyl-ATP pyrophosphohydrolase-like; In the N-terminal section; belongs to the PRA-CH family. | 0.635 |
| ADQ04113.1 | ilvC | Calow_0531 | Calow_0358 | TIGRFAM: threonine synthase; KEGG: ate:Athe_0655 threonine synthase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit. | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. | 0.621 |
| ADQ04113.1 | leuD | Calow_0531 | Calow_1786 | TIGRFAM: threonine synthase; KEGG: ate:Athe_0655 threonine synthase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit. | 3-isopropylmalate dehydratase, small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 2 subfamily. | 0.749 |
| ADQ04113.1 | thrB | Calow_0531 | Calow_1684 | TIGRFAM: threonine synthase; KEGG: ate:Athe_0655 threonine synthase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit. | Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. | 0.999 |
| ADQ04512.1 | ADQ03822.1 | Calow_0946 | Calow_0217 | PFAM: amino acid-binding ACT domain protein; KEGG: ate:Athe_1132 amino acid-binding ACT domain protein. | PFAM: homocysteine S-methyltransferase; methylenetetrahydrofolate reductase; KEGG: ate:Athe_0325 homocysteine S-methyltransferase. | 0.767 |
| ADQ04512.1 | ADQ04113.1 | Calow_0946 | Calow_0531 | PFAM: amino acid-binding ACT domain protein; KEGG: ate:Athe_1132 amino acid-binding ACT domain protein. | TIGRFAM: threonine synthase; KEGG: ate:Athe_0655 threonine synthase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit. | 0.710 |
| ADQ04512.1 | ADQ05228.1 | Calow_0946 | Calow_1683 | PFAM: amino acid-binding ACT domain protein; KEGG: ate:Athe_1132 amino acid-binding ACT domain protein. | PFAM: homoserine dehydrogenase; homoserine dehydrogenase NAD-binding; KEGG: ate:Athe_1959 homoserine dehydrogenase. | 0.758 |
