ADQ04166.1 protein (Caldicellulosiruptor owensensis)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

ADQ04166.1

KEGG: ate:Athe_0732 GTP-binding protein TypA; TIGRFAM: GTP-binding protein TypA; small GTP-binding protein; PFAM: protein synthesis factor GTP-binding; elongation factor Tu domain 2 protein; elongation factor G domain-containing protein. (616 aa)

Predicted Functional Partners:

guaA

0.766

ADQ04168.1

0.663

mltG

0.648

polA

0.618

infC

0.577

tig

0.574

ADQ04170.1

0.568

rpmI

0.563

rpsI

0.558

rplA

0.547

Your Current Organism:

Caldicellulosiruptor owensensis

NCBI taxonomy Id: 632518
Other names: C. owensensis OL, Caldicellulosiruptor owensensis DSM 13100, Caldicellulosiruptor owensensis OL, Caldicellulosiruptor owensensis str. OL, Caldicellulosiruptor owensensis strain OL

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc.

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ADQ04166.1	ADQ04168.1	Calow_0590	Calow_0592	KEGG: ate:Athe_0732 GTP-binding protein TypA; TIGRFAM: GTP-binding protein TypA; small GTP-binding protein; PFAM: protein synthesis factor GTP-binding; elongation factor Tu domain 2 protein; elongation factor G domain-containing protein.	PFAM: O-methyltransferase family 3; KEGG: ate:Athe_0734 O-methyltransferase family 3.	0.663
ADQ04166.1	ADQ04170.1	Calow_0590	Calow_0594	KEGG: ate:Athe_0732 GTP-binding protein TypA; TIGRFAM: GTP-binding protein TypA; small GTP-binding protein; PFAM: protein synthesis factor GTP-binding; elongation factor Tu domain 2 protein; elongation factor G domain-containing protein.	RNA polymerase, sigma 28 subunit, FliA/WhiG subfamily; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.	0.568
ADQ04166.1	guaA	Calow_0590	Calow_1210	KEGG: ate:Athe_0732 GTP-binding protein TypA; TIGRFAM: GTP-binding protein TypA; small GTP-binding protein; PFAM: protein synthesis factor GTP-binding; elongation factor Tu domain 2 protein; elongation factor G domain-containing protein.	GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP.	0.766
ADQ04166.1	infC	Calow_0590	Calow_0995	KEGG: ate:Athe_0732 GTP-binding protein TypA; TIGRFAM: GTP-binding protein TypA; small GTP-binding protein; PFAM: protein synthesis factor GTP-binding; elongation factor Tu domain 2 protein; elongation factor G domain-containing protein.	Translation initiation factor IF-3; IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.	0.577
ADQ04166.1	mltG	Calow_0590	Calow_0591	KEGG: ate:Athe_0732 GTP-binding protein TypA; TIGRFAM: GTP-binding protein TypA; small GTP-binding protein; PFAM: protein synthesis factor GTP-binding; elongation factor Tu domain 2 protein; elongation factor G domain-containing protein.	Aminodeoxychorismate lyase; Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation. Belongs to the transglycosylase MltG family.	0.648
ADQ04166.1	polA	Calow_0590	Calow_1220	KEGG: ate:Athe_0732 GTP-binding protein TypA; TIGRFAM: GTP-binding protein TypA; small GTP-binding protein; PFAM: protein synthesis factor GTP-binding; elongation factor Tu domain 2 protein; elongation factor G domain-containing protein.	DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.	0.618
ADQ04166.1	rplA	Calow_0590	Calow_1305	KEGG: ate:Athe_0732 GTP-binding protein TypA; TIGRFAM: GTP-binding protein TypA; small GTP-binding protein; PFAM: protein synthesis factor GTP-binding; elongation factor Tu domain 2 protein; elongation factor G domain-containing protein.	Ribosomal protein L1; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.	0.547
ADQ04166.1	rpmI	Calow_0590	Calow_0996	KEGG: ate:Athe_0732 GTP-binding protein TypA; TIGRFAM: GTP-binding protein TypA; small GTP-binding protein; PFAM: protein synthesis factor GTP-binding; elongation factor Tu domain 2 protein; elongation factor G domain-containing protein.	KEGG: ate:Athe_1205 ribosomal protein L35; TIGRFAM: ribosomal protein L35; PFAM: Ribosomal protein L35; Belongs to the bacterial ribosomal protein bL35 family.	0.563
ADQ04166.1	rpsI	Calow_0590	Calow_1751	KEGG: ate:Athe_0732 GTP-binding protein TypA; TIGRFAM: GTP-binding protein TypA; small GTP-binding protein; PFAM: protein synthesis factor GTP-binding; elongation factor Tu domain 2 protein; elongation factor G domain-containing protein.	PFAM: ribosomal protein S9; KEGG: ate:Athe_2069 ribosomal protein S9; Belongs to the universal ribosomal protein uS9 family.	0.558
ADQ04166.1	tig	Calow_0590	Calow_0577	KEGG: ate:Athe_0732 GTP-binding protein TypA; TIGRFAM: GTP-binding protein TypA; small GTP-binding protein; PFAM: protein synthesis factor GTP-binding; elongation factor Tu domain 2 protein; elongation factor G domain-containing protein.	Trigger factor; Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase; Belongs to the FKBP-type PPIase family. Tig subfamily.	0.574
ADQ04168.1	ADQ04166.1	Calow_0592	Calow_0590	PFAM: O-methyltransferase family 3; KEGG: ate:Athe_0734 O-methyltransferase family 3.	KEGG: ate:Athe_0732 GTP-binding protein TypA; TIGRFAM: GTP-binding protein TypA; small GTP-binding protein; PFAM: protein synthesis factor GTP-binding; elongation factor Tu domain 2 protein; elongation factor G domain-containing protein.	0.663
ADQ04168.1	ADQ04170.1	Calow_0592	Calow_0594	PFAM: O-methyltransferase family 3; KEGG: ate:Athe_0734 O-methyltransferase family 3.	RNA polymerase, sigma 28 subunit, FliA/WhiG subfamily; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.	0.710
ADQ04168.1	mltG	Calow_0592	Calow_0591	PFAM: O-methyltransferase family 3; KEGG: ate:Athe_0734 O-methyltransferase family 3.	Aminodeoxychorismate lyase; Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation. Belongs to the transglycosylase MltG family.	0.830
ADQ04170.1	ADQ04166.1	Calow_0594	Calow_0590	RNA polymerase, sigma 28 subunit, FliA/WhiG subfamily; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.	KEGG: ate:Athe_0732 GTP-binding protein TypA; TIGRFAM: GTP-binding protein TypA; small GTP-binding protein; PFAM: protein synthesis factor GTP-binding; elongation factor Tu domain 2 protein; elongation factor G domain-containing protein.	0.568
ADQ04170.1	ADQ04168.1	Calow_0594	Calow_0592	RNA polymerase, sigma 28 subunit, FliA/WhiG subfamily; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.	PFAM: O-methyltransferase family 3; KEGG: ate:Athe_0734 O-methyltransferase family 3.	0.710
ADQ04170.1	mltG	Calow_0594	Calow_0591	RNA polymerase, sigma 28 subunit, FliA/WhiG subfamily; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.	Aminodeoxychorismate lyase; Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation. Belongs to the transglycosylase MltG family.	0.710
guaA	ADQ04166.1	Calow_1210	Calow_0590	GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP.	KEGG: ate:Athe_0732 GTP-binding protein TypA; TIGRFAM: GTP-binding protein TypA; small GTP-binding protein; PFAM: protein synthesis factor GTP-binding; elongation factor Tu domain 2 protein; elongation factor G domain-containing protein.	0.766
guaA	infC	Calow_1210	Calow_0995	GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP.	Translation initiation factor IF-3; IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.	0.585
guaA	polA	Calow_1210	Calow_1220	GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP.	DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.	0.770
guaA	rplA	Calow_1210	Calow_1305	GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP.	Ribosomal protein L1; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.	0.947

page 1 of 4

Server load: low (12%) [HD]

Permalink

Network

Neighborhood

Experiments

Co-occurrence

Databases

Co-expression

Textmining

Fusion

© STRING Consortium 2026

Credits

Access

Info

About