Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
plsYProtein of unknown function DUF205; Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP. (202 aa)    
Predicted Functional Partners:
plsX
Fatty acid/phospholipid synthesis protein PlsX; Catalyzes the reversible formation of acyl-phosphate (acyl- PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
 
  
 0.986
ADQ03710.1
PFAM: protein of unknown function DUF205; KEGG: ate:Athe_0166 protein of unknown function DUF205; Belongs to the PlsY family.
  
  
 
0.927
ADQ04680.1
KEGG: ate:Athe_1326 phospholipid/glycerol acyltransferase; PFAM: phospholipid/glycerol acyltransferase; SMART: phospholipid/glycerol acyltransferase.
  
 
 0.922
ADQ03919.1
Carbohydrate kinase, FGGY-like protein; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate.
    
 0.911
ADQ04308.1
PFAM: FAD dependent oxidoreductase; BFD domain protein [2Fe-2S]-binding domain protein; KEGG: ate:Athe_0930 FAD dependent oxidoreductase.
    
 0.905
ADQ04953.1
TIGRFAM: glycerol-3-phosphate cytidylyltransferase; cytidyltransferase-related domain protein; KEGG: gtn:GTNG_3262 GNAT family protein; PFAM: cytidylyltransferase.
     
  0.900
ADQ04173.1
PFAM: protein of unknown function DUF512; KEGG: ate:Athe_0750 protein of unknown function DUF512.
       0.839
der
Ribosome-associated GTPase EngA; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
       0.839
ADQ04176.1
PFAM: Methyltransferase type 12; KEGG: ate:Athe_0753 methyltransferase type 11.
       0.781
ADQ04172.1
PFAM: dihydropteroate synthase DHPS; KEGG: ate:Athe_0749 dihydropteroate synthase DhpS.
       0.701
Your Current Organism:
Caldicellulosiruptor owensensis
NCBI taxonomy Id: 632518
Other names: C. owensensis OL, Caldicellulosiruptor owensensis DSM 13100, Caldicellulosiruptor owensensis OL, Caldicellulosiruptor owensensis str. OL, Caldicellulosiruptor owensensis strain OL
Server load: low (18%) [HD]