Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ADQ04224.1PFAM: 3-dehydroquinate synthase; KEGG: csc:Csac_0948 glutamate-1-semialdehyde 2,1-aminomutase. (405 aa)    
Predicted Functional Partners:
ADQ04308.1
PFAM: FAD dependent oxidoreductase; BFD domain protein [2Fe-2S]-binding domain protein; KEGG: ate:Athe_0930 FAD dependent oxidoreductase.
    
  0.902
araB
L-ribulokinase; KEGG: ate:Athe_2229 L-ribulokinase; TIGRFAM: L-ribulokinase; PFAM: Carbohydrate kinase, FGGY-like.
 
  
 0.824
ADQ04680.1
KEGG: ate:Athe_1326 phospholipid/glycerol acyltransferase; PFAM: phospholipid/glycerol acyltransferase; SMART: phospholipid/glycerol acyltransferase.
     
 0.815
ADQ04629.1
PFAM: diacylglycerol kinase; phosphoesterase PA-phosphatase related; KEGG: ate:Athe_1275 diacylglycerol kinase.
     
  0.800
ADQ05438.1
PFAM: class II aldolase/adducin family protein; KEGG: csc:Csac_0723 L-ribulose-5-phosphate 4-epimerase.
  
  
 0.670
cheB-3
Response regulator receiver modulated CheB methylesterase; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family.
       0.561
ADQ04222.1
KEGG: ate:Athe_0800 tetratricopeptide TPR_2 repeat protein; PFAM: Tetratricopeptide TPR_1 repeat-containing protein; Tetratricopeptide TPR_3 repeat-containing protein; SMART: Tetratricopeptide repeat.
 
     0.550
ADQ03815.1
HAD-superfamily hydrolase, subfamily IIA; Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro; Belongs to the HAD-like hydrolase superfamily. NagD family.
 
  
 0.540
thrS
threonyl-tRNA synthetase; Catalyzes the attachment of threonine to tRNA(Thr) in a two- step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr).
     
 0.530
ADQ04138.1
KEGG: ate:Athe_0697 hypothetical protein.
  
     0.515
Your Current Organism:
Caldicellulosiruptor owensensis
NCBI taxonomy Id: 632518
Other names: C. owensensis OL, Caldicellulosiruptor owensensis DSM 13100, Caldicellulosiruptor owensensis OL, Caldicellulosiruptor owensensis str. OL, Caldicellulosiruptor owensensis strain OL
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