Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ADQ04252.1Radical SAM domain protein; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate; Belongs to the radical SAM superfamily. MoaA family. (314 aa)    
Predicted Functional Partners:
ADQ04253.1
KEGG: ate:Athe_0830 molybdenum cofactor biosynthesis protein C; TIGRFAM: molybdenum cofactor biosynthesis protein C; PFAM: molybdopterin cofactor biosynthesis protein MoaC; MOSC domain containing protein.
 
 0.999
ADQ04250.1
Molybdenum cofactor synthesis domain protein; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family.
 
 0.980
ADQ04251.1
Molybdenum cofactor synthesis domain protein; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family.
 
 0.964
ADQ04010.1
PFAM: GTP cyclohydrolase II; 34-dihydroxy-2-butanone 4-phosphate synthase; KEGG: ate:Athe_0562 3,4-dihydroxy-2-butanone 4-phosphate synthase; In the N-terminal section; belongs to the DHBP synthase family.
    
 0.905
folE2
GTP cyclohydrolase I; Converts GTP to 7,8-dihydroneopterin triphosphate.
     
  0.900
ADQ04254.1
KEGG: ate:Athe_0831 molybdenum cofactor synthesis domain protein; TIGRFAM: molybdenum cofactor synthesis domain protein; PFAM: molybdopterin binding domain.
 
  
 0.888
ADQ04248.1
PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: ate:Athe_0825 binding-protein-dependent transport systems inner membrane component.
 
     0.886
ADQ04247.1
PFAM: extracellular solute-binding protein family 1; KEGG: ate:Athe_0824 extracellular solute-binding protein family 1.
 
   
 0.824
ADQ04106.1
KEGG: ate:Athe_0647 MazG family protein; TIGRFAM: MazG family protein; PFAM: MazG nucleotide pyrophosphohydrolase.
    
 0.812
ADQ03989.1
TIGRFAM: anaerobic ribonucleoside-triphosphate reductase; KEGG: ate:Athe_0548 anaerobic ribonucleoside-triphosphate reductase; PFAM: ATP-cone domain protein.
     
 0.808
Your Current Organism:
Caldicellulosiruptor owensensis
NCBI taxonomy Id: 632518
Other names: C. owensensis OL, Caldicellulosiruptor owensensis DSM 13100, Caldicellulosiruptor owensensis OL, Caldicellulosiruptor owensensis str. OL, Caldicellulosiruptor owensensis strain OL
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