Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
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Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ADQ04262.1KEGG: ate:Athe_0839 phosphodiesterase, MJ0936 family; TIGRFAM: phosphodiesterase, MJ0936 family; PFAM: metallophosphoesterase. (158 aa)    
Predicted Functional Partners:
ADQ04261.1
Non-canonical purine NTP pyrophosphatase, rdgB/HAM1 family; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.
  
  
 0.930
rph
Ribonuclease PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.
  
    0.848
ADQ04263.1
PFAM: GCN5-related N-acetyltransferase; KEGG: ate:Athe_0840 GCN5-related N-acetyltransferase.
  
  
 0.788
ADQ04259.1
PFAM: Lipoprotein LpqB, GerMN domain; KEGG: ate:Athe_0836 hypothetical protein.
       0.717
ADQ03633.1
Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.
   
 
 0.632
ADQ04265.1
KEGG: ate:Athe_0842 transcriptional regulator, DeoR family; PFAM: regulatory protein DeoR; SMART: regulatory protein DeoR.
     
 0.618
ADQ04264.1
PFAM: Carbohydrate kinase, FGGY-like; KEGG: ate:Athe_0841 carbohydrate kinase FGGY.
       0.615
ADQ03733.1
PFAM: esterase; KEGG: ate:Athe_0186 putative esterase.
  
  
 0.509
ADQ04257.1
KEGG: ate:Athe_0834 hypothetical protein.
       0.498
ADQ04258.1
PFAM: Glycosyl transferase, family 4, conserved region; KEGG: ate:Athe_0835 glycosyl transferase family 4.
       0.498
Your Current Organism:
Caldicellulosiruptor owensensis
NCBI taxonomy Id: 632518
Other names: C. owensensis OL, Caldicellulosiruptor owensensis DSM 13100, Caldicellulosiruptor owensensis OL, Caldicellulosiruptor owensensis str. OL, Caldicellulosiruptor owensensis strain OL
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