Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ADQ04264.1PFAM: Carbohydrate kinase, FGGY-like; KEGG: ate:Athe_0841 carbohydrate kinase FGGY. (473 aa)    
Predicted Functional Partners:
rhaA
TIGRFAM: L-rhamnose isomerase; KEGG: ate:Athe_0706 L-rhamnose isomerase; PFAM: L-rhamnose isomerase.
 
 
 0.990
ADQ04265.1
KEGG: ate:Athe_0842 transcriptional regulator, DeoR family; PFAM: regulatory protein DeoR; SMART: regulatory protein DeoR.
     
 0.798
rph
Ribonuclease PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.
     
 0.636
ADQ04261.1
Non-canonical purine NTP pyrophosphatase, rdgB/HAM1 family; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.
     
 0.622
ADQ04262.1
KEGG: ate:Athe_0839 phosphodiesterase, MJ0936 family; TIGRFAM: phosphodiesterase, MJ0936 family; PFAM: metallophosphoesterase.
       0.615
ADQ04263.1
PFAM: GCN5-related N-acetyltransferase; KEGG: ate:Athe_0840 GCN5-related N-acetyltransferase.
       0.615
ADQ04259.1
PFAM: Lipoprotein LpqB, GerMN domain; KEGG: ate:Athe_0836 hypothetical protein.
       0.565
ADQ04136.1
PFAM: class II aldolase/adducin family protein; KEGG: ate:Athe_0695 class II aldolase/adducin family protein.
 
  
 0.547
ADQ03695.1
KEGG: ate:Athe_0149 PTS system, fructose subfamily, IIC subunit; TIGRFAM: PTS system, fructose subfamily, IIC subunit; PTS system, fructose-specific, IIB subunnit; PFAM: phosphotransferase system EIIC.
     
 0.463
ADQ04431.1
TIGRFAM: ribulose-phosphate 3-epimerase; KEGG: ate:Athe_1047 ribulose-phosphate 3-epimerase; PFAM: ribulose-phosphate 3-epimerase.
    
 
 0.460
Your Current Organism:
Caldicellulosiruptor owensensis
NCBI taxonomy Id: 632518
Other names: C. owensensis OL, Caldicellulosiruptor owensensis DSM 13100, Caldicellulosiruptor owensensis OL, Caldicellulosiruptor owensensis str. OL, Caldicellulosiruptor owensensis strain OL
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