Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ADQ04268.1TIGRFAM: phospho-2-dehydro-3-deoxyheptonate aldolase; KEGG: ate:Athe_0845 phospho-2-dehydro-3-deoxyheptonate aldolase; PFAM: DAHP synthetase I/KDSA. (337 aa)    
Predicted Functional Partners:
aroB
3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
 
 
 0.991
aroA
3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
 
  
 0.950
pheA
KEGG: ate:Athe_0878 prephenate dehydratase; PFAM: prephenate dehydratase; amino acid-binding ACT domain protein.
 
  
 0.927
ADQ04267.1
PFAM: Prephenate dehydrogenase; KEGG: ate:Athe_0844 prephenate dehydrogenase.
  
 0.918
ADQ05568.1
PFAM: Transketolase domain-containing protein; Transketolase central region; KEGG: ate:Athe_2328 transketolase domain protein.
  
 
 0.847
tal
Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 3B subfamily.
    
 0.811
ADQ03917.1
PFAM: Transketolase domain-containing protein; KEGG: tna:CTN_1622 transketolase, N-terminal subunit.
    
  0.808
ADQ03918.1
PFAM: Transketolase central region; Transketolase domain-containing protein; KEGG: tna:CTN_1623 transketolase, C-terminal subunit.
    
  0.808
ADQ05279.1
PFAM: Transketolase central region; Transketolase domain-containing protein; KEGG: csc:Csac_1352 transketolase, central region.
    
  0.808
ADQ05280.1
PFAM: Transketolase domain-containing protein; KEGG: ate:Athe_2060 transketolase domain protein.
    
  0.808
Your Current Organism:
Caldicellulosiruptor owensensis
NCBI taxonomy Id: 632518
Other names: C. owensensis OL, Caldicellulosiruptor owensensis DSM 13100, Caldicellulosiruptor owensensis OL, Caldicellulosiruptor owensensis str. OL, Caldicellulosiruptor owensensis strain OL
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