Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ADQ04274.1KEGG: ate:Athe_2764 protein of unknown function UPF0236. (479 aa)    
Predicted Functional Partners:
ADQ04145.1
PFAM: Transketolase central region; dehydrogenase E1 component; Transketolase domain-containing protein; KEGG: ate:Athe_0704 transketolase central region.
  
  0.833
ADQ04429.1
KEGG: ate:Athe_1045 serine/threonine protein kinase with PASTA sensor(s); PFAM: Serine/threonine-protein kinase-like domain; PASTA domain containing protein; SMART: serine/threonine protein kinase; Tyrosine-protein kinase, catalytic domain; PASTA domain containing protein.
  
 
 0.701
ADQ04275.1
KEGG: ate:Athe_0853 two component transcriptional regulator, AraC family; PFAM: response regulator receiver; helix-turn-helix- domain containing protein AraC type; SMART: Helix-turn-helix, AraC domain; response regulator receiver.
       0.592
ADQ04426.1
Sun protein; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.
  
   0.547
ADQ04415.1
PFAM: histone deacetylase superfamily; KEGG: ate:Athe_1031 histone deacetylase superfamily.
   
   0.492
ADQ04966.1
TIGRFAM: Flagellar operon protein YvyF; KEGG: ate:Athe_1678 hypothetical protein.
   
   0.489
ADQ04222.1
KEGG: ate:Athe_0800 tetratricopeptide TPR_2 repeat protein; PFAM: Tetratricopeptide TPR_1 repeat-containing protein; Tetratricopeptide TPR_3 repeat-containing protein; SMART: Tetratricopeptide repeat.
    
   0.483
ADQ04276.1
Alpha-glucuronidase; KEGG: ate:Athe_0854 alpha-glucuronidase; PFAM: Glycosyl hydrolase 67 middle domain protein; glycosyl hydrolase 67 C-teriminal domain protein.
       0.460
ADQ04277.1
KEGG: ate:Athe_0855 mannitol dehydrogenase domain protein; manually curated; PFAM: Mannitol dehydrogenase domain; Mannitol dehydrogenase rossman domain.
 
     0.460
ADQ04273.1
Integral membrane sensor signal transduction histidine kinase; KEGG: ate:Athe_0852 putative sensor with HAMP domain; PFAM: histidine kinase internal region; histidine kinase HAMP region domain protein; ATP-binding region ATPase domain protein; SMART: histidine kinase HAMP region domain protein.
       0.457
Your Current Organism:
Caldicellulosiruptor owensensis
NCBI taxonomy Id: 632518
Other names: C. owensensis OL, Caldicellulosiruptor owensensis DSM 13100, Caldicellulosiruptor owensensis OL, Caldicellulosiruptor owensensis str. OL, Caldicellulosiruptor owensensis strain OL
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.