Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ADQ04277.1KEGG: ate:Athe_0855 mannitol dehydrogenase domain protein; manually curated; PFAM: Mannitol dehydrogenase domain; Mannitol dehydrogenase rossman domain. (539 aa)    
Predicted Functional Partners:
uxuA
Mannonate dehydratase; Catalyzes the dehydration of D-mannonate.
 
 
 0.996
uxaC
KEGG: csc:Csac_1949 glucuronate isomerase; PFAM: Glucuronate isomerase.
 
 
 0.984
ADQ04276.1
Alpha-glucuronidase; KEGG: ate:Athe_0854 alpha-glucuronidase; PFAM: Glycosyl hydrolase 67 middle domain protein; glycosyl hydrolase 67 C-teriminal domain protein.
 
   
 0.716
ADQ03695.1
KEGG: ate:Athe_0149 PTS system, fructose subfamily, IIC subunit; TIGRFAM: PTS system, fructose subfamily, IIC subunit; PTS system, fructose-specific, IIB subunnit; PFAM: phosphotransferase system EIIC.
  
  
 0.521
tpiA
Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family.
     
 0.509
ADQ04275.1
KEGG: ate:Athe_0853 two component transcriptional regulator, AraC family; PFAM: response regulator receiver; helix-turn-helix- domain containing protein AraC type; SMART: Helix-turn-helix, AraC domain; response regulator receiver.
  
    0.492
ADQ05629.1
KEGG: csc:Csac_0354 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase; TIGRFAM: 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase; PFAM: KDPG and KHG aldolase.
 
  
 0.486
ADQ04279.1
PFAM: glycoside hydrolase family 2 sugar binding; glycoside hydrolase family 2 immunoglobulin domain protein beta-sandwich; glycoside hydrolase family 2 TIM barrel; KEGG: ate:Athe_0857 glycoside hydrolase family 2 sugar binding; Belongs to the glycosyl hydrolase 2 family.
     
 0.483
ADQ04274.1
KEGG: ate:Athe_2764 protein of unknown function UPF0236.
 
     0.460
ADQ03694.1
KEGG: ate:Athe_0148 putative PTS IIA-like nitrogen-regulatory protein PtsN; TIGRFAM: PTS system, fructose subfamily, IIA subunit; PFAM: phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2.
  
  
 0.416
Your Current Organism:
Caldicellulosiruptor owensensis
NCBI taxonomy Id: 632518
Other names: C. owensensis OL, Caldicellulosiruptor owensensis DSM 13100, Caldicellulosiruptor owensensis OL, Caldicellulosiruptor owensensis str. OL, Caldicellulosiruptor owensensis strain OL
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