Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
ADQ04354.1PFAM: Protein of unknown function DUF2273; KEGG: ate:Athe_1000 hypothetical protein. (69 aa)    
Predicted Functional Partners:
ADQ04353.1
KEGG: ate:Athe_0999 hypothetical protein.
 
     0.928
nusB
NusB antitermination factor; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.
       0.714
ADQ04352.1
PFAM: protein of unknown function DUF322; KEGG: ate:Athe_0998 protein of unknown function DUF322.
       0.711
ADQ04351.1
KEGG: ate:Athe_0997 hypothetical protein.
 
     0.700
xseA
Exodeoxyribonuclease VII, large subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseA family.
       0.697
ADQ04358.1
PFAM: Polyprenyl synthetase; KEGG: ate:Athe_1004 polyprenyl synthetase; Belongs to the FPP/GGPP synthase family.
       0.692
xseB
Exodeoxyribonuclease VII, small subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseB family.
       0.685
ADQ04350.1
KEGG: ate:Athe_0996 hypothetical protein.
 
     0.628
ADQ04925.1
KEGG: ate:Athe_1629 hypothetical protein.
  
     0.549
ADQ04349.1
PFAM: Sporulation stage III protein AF; KEGG: ate:Athe_0995 hypothetical protein.
       0.541
Your Current Organism:
Caldicellulosiruptor owensensis
NCBI taxonomy Id: 632518
Other names: C. owensensis OL, Caldicellulosiruptor owensensis DSM 13100, Caldicellulosiruptor owensensis OL, Caldicellulosiruptor owensensis str. OL, Caldicellulosiruptor owensensis strain OL
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