Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ADQ04387.1AAA ATPase; KEGG: tit:Thit_1404 AAA ATPase; manually curated; SMART: AAA ATPase. (266 aa)    
Predicted Functional Partners:
ADQ04294.1
Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily.
  
 
 0.889
ADQ04386.1
Hypothetical protein; KEGG: lsp:Bsph_1775 phage replication protein.
  
  
 0.834
ADQ03788.1
KEGG: ate:Athe_0244 SpoIID/LytB domain protein; TIGRFAM: SpoIID/LytB domain protein; PFAM: Stage II sporulation protein D.
  
    0.721
ADQ04391.1
PFAM: endodeoxyribonuclease RusA; KEGG: ate:Athe_2445 endodeoxyribonuclease RusA.
  
  
 0.708
ADQ04390.1
RNA polymerase, sigma 70 subunit, RpoD subfamily; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
       0.695
ADQ04388.1
KEGG: drm:Dred_2612 hypothetical protein.
       0.689
ADQ04389.1
Hypothetical protein.
       0.689
ADQ04392.1
Hypothetical protein; Manually curated; KEGG: cbi:CLJ_B0158 cyanophycin synthetase.
       0.657
dnaA
Chromosomal replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family.
    
 
 0.642
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
     
 0.617
Your Current Organism:
Caldicellulosiruptor owensensis
NCBI taxonomy Id: 632518
Other names: C. owensensis OL, Caldicellulosiruptor owensensis DSM 13100, Caldicellulosiruptor owensensis OL, Caldicellulosiruptor owensensis str. OL, Caldicellulosiruptor owensensis strain OL
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