Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ADQ04449.1N-acetylmuramoyl-L-alanine amidase; SMART: cell wall hydrolase/autolysin; manually curated; KEGG: ate:Athe_1064 N-acetylmuramoyl-L-alanine amidase; PFAM: cell wall hydrolase/autolysin. (190 aa)    
Predicted Functional Partners:
ADQ04465.1
KEGG: ate:Athe_1080 cell wall hydrolase/autolysin; PFAM: cell wall hydrolase/autolysin; copper amine oxidase-like domain-containing protein; SMART: cell wall hydrolase/autolysin.
  
  
 
0.918
ADQ03865.1
KEGG: ate:Athe_0430 cell wall hydrolase/autolysin; PFAM: cell wall hydrolase/autolysin; SMART: cell wall hydrolase/autolysin.
  
  
 
0.916
ADQ05724.1
PFAM: Rhomboid family protein; KEGG: ate:Athe_2713 rhomboid family protein.
   
   0.764
ADQ05090.1
Peptidase M23; KEGG: ate:Athe_1799 peptidase M23; manually curated; PFAM: Peptidase M23.
 
   0.674
ADQ04450.1
KEGG: ate:Athe_1065 8-oxoguanine DNA glycosylase domain protein; PFAM: 8-oxoguanine DNA glycosylase domain-containing protein; HhH-GPD family protein; SMART: HhH-GPD family protein.
       0.533
cinA
KEGG: ate:Athe_0985 competence/damage-inducible protein CinA; TIGRFAM: competence/damage-inducible protein CinA; PFAM: CinA domain protein; molybdopterin binding domain; Belongs to the CinA family.
 
     0.523
ADQ04451.1
KEGG: ate:Athe_1066 hypothetical protein.
       0.470
ADQ03763.1
KEGG: ate:Athe_0218 stage II sporulation protein D; TIGRFAM: stage II sporulation protein D; SpoIID/LytB domain protein; PFAM: Stage II sporulation protein D.
  
 0.462
nnrE
Carbohydrate kinase, YjeF related protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow t [...]
 
   
 0.458
ADQ04452.1
PFAM: major facilitator superfamily MFS_1; KEGG: ate:Athe_1067 major facilitator superfamily MFS_1.
       0.424
Your Current Organism:
Caldicellulosiruptor owensensis
NCBI taxonomy Id: 632518
Other names: C. owensensis OL, Caldicellulosiruptor owensensis DSM 13100, Caldicellulosiruptor owensensis OL, Caldicellulosiruptor owensensis str. OL, Caldicellulosiruptor owensensis strain OL
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