Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ADQ04459.1PFAM: zinc/iron permease; KEGG: ate:Athe_1074 zinc/iron permease. (245 aa)    
Predicted Functional Partners:
ADQ04460.1
Sua5/YciO/YrdC/YwlC family protein; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.
       0.817
ADQ04461.1
KEGG: ate:Athe_1076 protein tyrosine phosphatase; PFAM: Protein-tyrosine phosphatase, low molecular weight; SMART: Protein-tyrosine phosphatase, low molecular weight.
       0.817
rlmH
Protein of unknown function DUF163; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA; Belongs to the RNA methyltransferase RlmH family.
       0.789
ADQ05501.1
KEGG: ate:Athe_2280 heavy metal translocating P-type ATPase; TIGRFAM: heavy metal translocating P-type ATPase; copper-translocating P-type ATPase; copper ion binding protein; cadmium-translocating P-type ATPase; ATPase, P-type (transporting), HAD superfamily, subfamily IC; PFAM: E1-E2 ATPase-associated domain protein; Heavy metal transport/detoxification protein; Haloacid dehalogenase domain protein hydrolase.
 
   
 0.660
ADQ05161.1
PFAM: cytochrome c biogenesis protein transmembrane region; KEGG: ate:Athe_1899 cytochrome c biogenesis protein transmembrane region.
   
    0.534
prmC
protein-(glutamine-N5) methyltransferase, release factor-specific; Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif; Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
  
    0.533
ADQ04457.1
PFAM: MotA/TolQ/ExbB proton channel; KEGG: ate:Athe_1072 MotA/TolQ/ExbB proton channel.
       0.533
ADQ04458.1
PFAM: OmpA/MotB domain protein; KEGG: ate:Athe_1073 OmpA/MotB domain protein.
       0.533
prfA
Peptide chain release factor 1; Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
  
    0.529
ADQ04454.1
PFAM: protein of unknown function DUF1385; KEGG: ate:Athe_1069 protein of unknown function DUF1385.
       0.496
Your Current Organism:
Caldicellulosiruptor owensensis
NCBI taxonomy Id: 632518
Other names: C. owensensis OL, Caldicellulosiruptor owensensis DSM 13100, Caldicellulosiruptor owensensis OL, Caldicellulosiruptor owensensis str. OL, Caldicellulosiruptor owensensis strain OL
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