Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ADQ04466.1KEGG: ate:Athe_1081 Cof-like hydrolase; TIGRFAM: Cof-like hydrolase; HAD-superfamily hydrolase, subfamily IIB; PFAM: Haloacid dehalogenase domain protein hydrolase type 3. (284 aa)    
Predicted Functional Partners:
ADQ04468.1
PFAM: respiratory-chain NADH dehydrogenase subunit 1; KEGG: ate:Athe_1083 respiratory-chain NADH dehydrogenase subunit 1.
 
     0.577
ADQ04470.1
PFAM: NADH dehydrogenase (ubiquinone) 30 kDa subunit; KEGG: ate:Athe_1085 NADH dehydrogenase (ubiquinone) 30 kDa subunit.
 
     0.528
ADQ04467.1
PFAM: NADH/Ubiquinone/plastoquinone (complex I); NADH-Ubiquinone oxidoreductase (complex I) chain 5/L domain protein; KEGG: ate:Athe_1082 NADH dehydrogenase (quinone).
       0.509
ADQ04469.1
PFAM: NADH ubiquinone oxidoreductase 20 kDa subunit; KEGG: ate:Athe_1084 NADH ubiquinone oxidoreductase 20 kDa subunit.
       0.467
ADQ04471.1
PFAM: NADH-ubiquinone oxidoreductase chain 49kDa; nickel-dependent hydrogenase large subunit; KEGG: ate:Athe_1086 NADH-ubiquinone oxidoreductase chain 49kDa.
       0.467
ADQ04472.1
KEGG: ate:Athe_1087 4Fe-4S ferredoxin iron-sulfur binding domain protein.
  
    0.425
ADQ04620.1
KEGG: ate:Athe_1266 pyruvate kinase; TIGRFAM: pyruvate kinase; PFAM: Pyruvate kinase barrel; Pyruvate kinase alpha/beta; PEP-utilising protein mobile region.
  
 
 0.415
Your Current Organism:
Caldicellulosiruptor owensensis
NCBI taxonomy Id: 632518
Other names: C. owensensis OL, Caldicellulosiruptor owensensis DSM 13100, Caldicellulosiruptor owensensis OL, Caldicellulosiruptor owensensis str. OL, Caldicellulosiruptor owensensis strain OL
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