Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ADQ04478.1KEGG: ate:Athe_1093 hydrogenase expression/formation protein HypE; TIGRFAM: hydrogenase expression/formation protein HypE; PFAM: AIR synthase related protein domain protein; AIR synthase related protein. (333 aa)    
Predicted Functional Partners:
ADQ04477.1
KEGG: ate:Athe_1092 hydrogenase formation HypD protein; TIGRFAM: hydrogenase expression/formation protein HypD; PFAM: hydrogenase formation HypD protein.
 
 
 0.996
ADQ04475.1
KEGG: ate:Athe_1090 (NiFe) hydrogenase maturation protein HypF; TIGRFAM: [NiFe] hydrogenase maturation protein HypF; PFAM: SUA5/yciO/yrdC domain; acylphosphatase.
 
 
 0.995
ADQ04476.1
KEGG: ate:Athe_1091 hydrogenase assembly chaperone HypC/HupF; TIGRFAM: hydrogenase assembly chaperone hypC/hupF; PFAM: hydrogenase expression/formation protein (HUPF/HYPC).
 
 
 0.989
hypA
Hydrogenase nickel insertion protein HypA; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
 
  
 0.960
ADQ04474.1
KEGG: ate:Athe_1089 hydrogenase accessory protein HypB; TIGRFAM: hydrogenase accessory protein HypB; PFAM: cobalamin synthesis protein P47K.
 
  
 0.959
ADQ04479.1
KEGG: ate:Athe_1094 hypothetical protein.
       0.661
ADQ04480.1
KEGG: ate:Athe_1095 4Fe-4S ferredoxin iron-sulfur binding domain protein.
     
 0.629
ADQ04481.1
PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; KEGG: ate:Athe_1096 pyruvate flavodoxin/ferredoxin oxidoreductase domain protein.
     
 0.621
ADQ04472.1
KEGG: ate:Athe_1087 4Fe-4S ferredoxin iron-sulfur binding domain protein.
  
  
 0.619
ADQ04469.1
PFAM: NADH ubiquinone oxidoreductase 20 kDa subunit; KEGG: ate:Athe_1084 NADH ubiquinone oxidoreductase 20 kDa subunit.
     
 0.567
Your Current Organism:
Caldicellulosiruptor owensensis
NCBI taxonomy Id: 632518
Other names: C. owensensis OL, Caldicellulosiruptor owensensis DSM 13100, Caldicellulosiruptor owensensis OL, Caldicellulosiruptor owensensis str. OL, Caldicellulosiruptor owensensis strain OL
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