Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ADQ04485.1PFAM: Protein of unknown function DUF2225; KEGG: ate:Athe_1100 hypothetical protein. (221 aa)    
Predicted Functional Partners:
ADQ04484.1
PFAM: VanW family protein; G5 domain protein; KEGG: ate:Athe_1099 VanW family protein.
 
     0.819
ADQ04482.1
PFAM: thiamine pyrophosphate TPP-binding domain-containing protein; KEGG: ate:Athe_1097 thiamine pyrophosphate protein domain protein TPP-binding.
       0.726
ADQ04483.1
PFAM: Pyruvate/ketoisovalerate oxidoreductase, catalytic domain; KEGG: ate:Athe_1098 pyruvate ferredoxin/flavodoxin oxidoreductase.
       0.726
ADQ05353.1
PFAM: CheC domain protein; KEGG: ate:Athe_2134 CheC domain protein.
 
     0.720
ADQ05362.1
KEGG: ate:Athe_2143 protein of unknown function DUF342; manually curated; PFAM: protein of unknown function DUF342.
 
     0.696
ADQ05369.1
PFAM: type IV pilus assembly PilZ; KEGG: ate:Athe_2150 type IV pilus assembly PilZ.
  
     0.696
ADQ05443.1
PFAM: CheC domain protein; KEGG: ate:Athe_2232 CheC domain protein.
 
     0.680
ADQ03957.1
PFAM: protein of unknown function DUF327; KEGG: ate:Athe_0514 protein of unknown function DUF327.
 
     0.665
ADQ04965.1
KEGG: ate:Athe_1677 anti-sigma-28 factor, FlgM; TIGRFAM: Anti-sigma-28 factor FlgM family protein; PFAM: Anti-sigma-28 factor FlgM family protein.
  
     0.639
ADQ04486.1
KEGG: csc:Csac_1554 hypothetical protein.
 
     0.615
Your Current Organism:
Caldicellulosiruptor owensensis
NCBI taxonomy Id: 632518
Other names: C. owensensis OL, Caldicellulosiruptor owensensis DSM 13100, Caldicellulosiruptor owensensis OL, Caldicellulosiruptor owensensis str. OL, Caldicellulosiruptor owensensis strain OL
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