Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ADQ04517.1PFAM: NurA domain; KEGG: ate:Athe_1138 hypothetical protein. (391 aa)    
Predicted Functional Partners:
ADQ04519.1
KEGG: ate:Athe_1140 protein of unknown function DUF87.
 
 
 
 0.988
ADQ04518.1
KEGG: ate:Athe_1139 hypothetical protein.
 
     0.942
sbcD
Nuclease SbcCD, D subunit; SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity; Belongs to the SbcD family.
 
     0.915
ADQ04521.1
PFAM: SMC domain protein; KEGG: ate:Athe_1142 SMC domain protein.
 
   
 0.914
ADQ04452.1
PFAM: major facilitator superfamily MFS_1; KEGG: ate:Athe_1067 major facilitator superfamily MFS_1.
  
     0.670
ADQ03873.1
PFAM: S-layer domain-containing protein; KEGG: ate:Athe_0438 S-layer domain protein.
  
     0.660
ADQ05212.1
PFAM: Fibronectin type III domain protein; KEGG: ate:Athe_1944 fibronectin type III domain protein.
  
     0.621
ADQ04160.1
KEGG: ate:Athe_0715 hypothetical protein.
  
     0.620
ADQ05582.1
PFAM: S-layer domain-containing protein; KEGG: ate:Athe_2342 S-layer domain protein.
  
     0.610
ADQ04571.1
PFAM: NUDIX hydrolase; KEGG: ate:Athe_1217 NUDIX hydrolase.
  
     0.603
Your Current Organism:
Caldicellulosiruptor owensensis
NCBI taxonomy Id: 632518
Other names: C. owensensis OL, Caldicellulosiruptor owensensis DSM 13100, Caldicellulosiruptor owensensis OL, Caldicellulosiruptor owensensis str. OL, Caldicellulosiruptor owensensis strain OL
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