Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
tmcALProtein of unknown function DUF795; Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of elongator tRNA(Met), using acetate and ATP as substrates. First activates an acetate ion to form acetyladenylate (Ac- AMP) and then transfers the acetyl group to tRNA to form ac(4)C34. (400 aa)    
Predicted Functional Partners:
ADQ03717.1
KEGG: ate:Athe_0171 O-methyltransferase-like protein; Belongs to the methyltransferase superfamily.
 
     0.748
polC
DNA polymerase III, alpha subunit; Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity.
  
     0.647
ADQ04176.1
PFAM: Methyltransferase type 12; KEGG: ate:Athe_0753 methyltransferase type 11.
  
    0.589
ADQ04292.1
Phosphoesterase RecJ domain protein; Has phosphodiesterase (PDE) activity against cyclic-di-AMP (c-di-AMP); Belongs to the GdpP/PdeA phosphodiesterase family.
  
     0.580
ADQ04605.1
TIGRFAM: metal dependent phophohydrolase; PFAM: metal-dependent phosphohydrolase HD sub domain; KEGG: ate:Athe_1251 metal dependent phosphohydrolase; SMART: metal-dependent phosphohydrolase HD region.
 
  
 0.520
ADQ04586.1
PFAM: acyl-CoA dehydrogenase domain-containing protein; KEGG: ate:Athe_1232 acyl-CoA dehydrogenase domain protein.
       0.501
ADQ04587.1
PFAM: Electron transfer flavoprotein alpha/beta-subunit; KEGG: ate:Athe_1233 electron transfer flavoprotein alpha/beta-subunit.
       0.438
Your Current Organism:
Caldicellulosiruptor owensensis
NCBI taxonomy Id: 632518
Other names: C. owensensis OL, Caldicellulosiruptor owensensis DSM 13100, Caldicellulosiruptor owensensis OL, Caldicellulosiruptor owensensis str. OL, Caldicellulosiruptor owensensis strain OL
Server load: low (16%) [HD]