Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ADQ04592.1TIGRFAM: nucleotide sugar dehydrogenase; KEGG: ate:Athe_1238 nucleotide sugar dehydrogenase; PFAM: UDP-glucose/GDP-mannose dehydrogenase; UDP-glucose/GDP-mannose dehydrogenase dimerisation; UDP-glucose/GDP-mannose dehydrogenase. (437 aa)    
Predicted Functional Partners:
ADQ04593.1
PFAM: oxidoreductase domain protein; Oxidoreductase domain; KEGG: ate:Athe_1239 oxidoreductase domain protein.
 
 
 0.987
ADQ05214.1
TIGRFAM: UDP-N-acetylglucosamine 2-epimerase; KEGG: ate:Athe_1946 UDP-N-acetylglucosamine 2-epimerase; PFAM: UDP-N-acetylglucosamine 2-epimerase.
 
 
 0.980
ADQ05574.1
PFAM: oxidoreductase domain protein; Oxidoreductase domain; KEGG: ate:Athe_2334 oxidoreductase domain protein.
 
 
 0.941
ADQ04591.1
PFAM: DegT/DnrJ/EryC1/StrS aminotransferase; KEGG: ate:Athe_1237 glutamine--scyllo-inositol transaminase.
 
  
 0.927
glmU
UDP-N-acetylglucosamine pyrophosphorylase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain.
  
 
 0.921
ADQ04597.1
PFAM: glycosyl transferase group 1; KEGG: ate:Athe_1243 glycosyl transferase group 1.
 
  
 0.916
ADQ04594.1
KEGG: ate:Athe_1240 hexapaptide repeat-containing transferase.
 
  
 0.877
ADQ03900.1
PFAM: glycosyl transferase group 1; KEGG: ate:Athe_0461 glycosyl transferase group 1.
 
  
 0.772
ADQ04596.1
KEGG: ate:Athe_1242 hypothetical protein.
 
     0.738
ADQ04595.1
KEGG: ate:Athe_1241 hypothetical protein.
       0.684
Your Current Organism:
Caldicellulosiruptor owensensis
NCBI taxonomy Id: 632518
Other names: C. owensensis OL, Caldicellulosiruptor owensensis DSM 13100, Caldicellulosiruptor owensensis OL, Caldicellulosiruptor owensensis str. OL, Caldicellulosiruptor owensensis strain OL
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