Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
ADQ04621.1PFAM: thioesterase superfamily protein; KEGG: ate:Athe_1267 thioesterase superfamily protein. (139 aa)    
Predicted Functional Partners:
ADQ04620.1
KEGG: ate:Athe_1266 pyruvate kinase; TIGRFAM: pyruvate kinase; PFAM: Pyruvate kinase barrel; Pyruvate kinase alpha/beta; PEP-utilising protein mobile region.
       0.791
pfkA
6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
       0.726
acpP
Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis.
  
 
 0.662
ADQ04618.1
KEGG: csc:Csac_1829 hypothetical protein.
       0.655
rpsU
KEGG: csc:Csac_1833 ribosomal protein S21; TIGRFAM: ribosomal protein S21; PFAM: ribosomal protein S21; Belongs to the bacterial ribosomal protein bS21 family.
  
    0.570
ADQ04617.1
PFAM: tryptophan RNA-binding attenuator protein; KEGG: ate:Athe_1263 tryptophan RNA-binding attenuator protein.
       0.562
ADQ04616.1
DNA polymerase III, alpha subunit; SMART: phosphoesterase PHP domain protein; TIGRFAM: DNA polymerase III, alpha subunit; KEGG: ate:Athe_1262 DNA polymerase III, alpha subunit; PFAM: DNA polymerase III alpha subunit; PHP domain protein; nucleic acid binding OB-fold tRNA/helicase-type.
       0.544
secA
Preprotein translocase, SecA subunit; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane; Belongs to the SecA family.
   
   0.518
ADQ04623.1
KEGG: ate:Athe_1269 GatB/YqeY domain-containing protein.
       0.505
ADQ05391.1
KEGG: ate:Athe_2172 flagellar motor switch protein FliG; TIGRFAM: flagellar motor switch protein FliG; PFAM: flagellar motor switch protein FliG; MgtE intracellular region.
    
   0.504
Your Current Organism:
Caldicellulosiruptor owensensis
NCBI taxonomy Id: 632518
Other names: C. owensensis OL, Caldicellulosiruptor owensensis DSM 13100, Caldicellulosiruptor owensensis OL, Caldicellulosiruptor owensensis str. OL, Caldicellulosiruptor owensensis strain OL
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