Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ybeYProtein of unknown function UPF0054; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA. (158 aa)    
Predicted Functional Partners:
ADQ04626.1
PFAM: PhoH family protein; K Homology, type 1, subgroup; KEGG: ate:Athe_1272 PhoH family protein.
  
  
 0.985
ADQ04629.1
PFAM: diacylglycerol kinase; phosphoesterase PA-phosphatase related; KEGG: ate:Athe_1275 diacylglycerol kinase.
 
  
 0.985
era
GTP-binding protein Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
  
 0.979
ADQ04627.1
7TM receptor with intracellular metal dependent phosphohydrolase; TIGRFAM: metal dependent phophohydrolase; PFAM: metal-dependent phosphohydrolase HD sub domain; metal-dependent phosphohydrolase 7TM intracellular region; KEGG: ate:Athe_1273 metal dependent phosphohydrolase; SMART: metal-dependent phosphohydrolase HD region.
  
  
 0.860
rplQ
KEGG: ate:Athe_1716 ribosomal protein L17; TIGRFAM: ribosomal protein L17; PFAM: ribosomal protein L17.
 
 
 
 0.850
ADQ05066.1
Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family.
 
  
 0.805
rpsQ
30S ribosomal protein S17; One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
   
 
 0.802
ADQ04630.1
KEGG: ate:Athe_1276 hypothetical protein.
  
    0.792
rplU
Ribosomal protein L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family.
   
 
 0.791
ADQ04625.1
PFAM: stage IV sporulation YqfD; KEGG: ate:Athe_1271 hypothetical protein.
       0.789
Your Current Organism:
Caldicellulosiruptor owensensis
NCBI taxonomy Id: 632518
Other names: C. owensensis OL, Caldicellulosiruptor owensensis DSM 13100, Caldicellulosiruptor owensensis OL, Caldicellulosiruptor owensensis str. OL, Caldicellulosiruptor owensensis strain OL
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