Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ADQ04643.1TIGRFAM: hemolysin A; PFAM: RNA-binding S4 domain protein; ribosomal RNA methyltransferase RrmJ/FtsJ; KEGG: ate:Athe_1289 hemolysin A; SMART: RNA-binding S4 domain protein. (269 aa)    
Predicted Functional Partners:
dxs
Deoxyxylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily.
  
    0.916
ADQ04641.1
KEGG: ate:Athe_1287 hypothetical protein.
     
 0.817
ADQ04644.1
KEGG: ate:Athe_1290 hypothetical protein.
       0.717
ADQ04645.1
PFAM: ATP-binding region ATPase domain protein; KEGG: ate:Athe_1291 putative anti-sigma regulatory factor, serine/threonine protein kinase.
       0.716
ADQ04358.1
PFAM: Polyprenyl synthetase; KEGG: ate:Athe_1004 polyprenyl synthetase; Belongs to the FPP/GGPP synthase family.
 
    0.682
ADQ04646.1
PFAM: Fe-S cluster domain protein; KEGG: ate:Athe_1292 Fe-S cluster domain protein.
       0.617
ADQ04648.1
KEGG: ate:Athe_1294 PHP domain protein; PFAM: PHP domain protein; SMART: phosphoesterase PHP domain protein.
       0.614
nadK
ATP-NAD/AcoX kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
  
  
 0.607
ADQ04647.1
KEGG: ate:Athe_1293 hypothetical protein.
       0.605
nusB
NusB antitermination factor; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.
 
    0.474
Your Current Organism:
Caldicellulosiruptor owensensis
NCBI taxonomy Id: 632518
Other names: C. owensensis OL, Caldicellulosiruptor owensensis DSM 13100, Caldicellulosiruptor owensensis OL, Caldicellulosiruptor owensensis str. OL, Caldicellulosiruptor owensensis strain OL
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