Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ADQ04653.1KEGG: ate:Athe_1299 hydrogenase, Fe-only; TIGRFAM: hydrogenase, Fe-only; PFAM: hydrogenase large subunit domain protein; NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding; ferredoxin; iron hydrogenase small subunit. (579 aa)    
Predicted Functional Partners:
ADQ04649.1
PFAM: NADH dehydrogenase (ubiquinone) 24 kDa subunit; KEGG: ate:Athe_1295 NADH dehydrogenase (ubiquinone) 24 kDa subunit.
 
 0.999
ADQ04652.1
KEGG: ate:Athe_1298 NADH dehydrogenase (quinone); PFAM: Respiratory-chain NADH dehydrogenase domain 51 kDa subunit; Sucraseferredoxin family protein; Soluble ligand binding domain; NADH ubiquinone oxidoreductase, F subunit, iron sulphur binding.
 
 
 0.998
ADQ04651.1
KEGG: ate:Athe_1297 hypothetical protein.
 
 
 0.994
ADQ04998.1
KEGG: ate:Athe_1709 pyruvate/ketoisovalerate oxidoreductase, gamma subunit; TIGRFAM: pyruvate/ketoisovalerate oxidoreductase, gamma subunit; PFAM: Pyruvate/ketoisovalerate oxidoreductase, catalytic domain.
 
 
 0.971
ADQ05435.1
KEGG: ate:Athe_2219 4Fe-4S ferredoxin iron-sulfur binding domain protein.
  
 
 0.965
ADQ05354.1
KEGG: ate:Athe_2135 protein of unknown function DUF362.
  
 
 0.951
ADQ04472.1
KEGG: ate:Athe_1087 4Fe-4S ferredoxin iron-sulfur binding domain protein.
  
 
 0.946
ADQ04103.1
KEGG: ate:Athe_0644 glutamate synthase (NADPH), homotetrameric; TIGRFAM: glutamate synthase (NADPH), homotetrameric; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase.
    
 0.906
ADQ04569.1
KEGG: ate:Athe_1215 nitrate reductase; PFAM: molybdopterin oxidoreductase Fe4S4 region; molybdopterin oxidoreductase; molydopterin dinucleotide-binding region; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
 
  
 0.904
ADQ04646.1
PFAM: Fe-S cluster domain protein; KEGG: ate:Athe_1292 Fe-S cluster domain protein.
 
 
 
0.884
Your Current Organism:
Caldicellulosiruptor owensensis
NCBI taxonomy Id: 632518
Other names: C. owensensis OL, Caldicellulosiruptor owensensis DSM 13100, Caldicellulosiruptor owensensis OL, Caldicellulosiruptor owensensis str. OL, Caldicellulosiruptor owensensis strain OL
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