Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ADQ04670.1PFAM: carboxyl transferase; KEGG: ate:Athe_1316 carboxyl transferase. (514 aa)    
Predicted Functional Partners:
ADQ05519.1
PFAM: biotin/lipoyl attachment domain-containing protein; KEGG: csc:Csac_2483 biotin/lipoyl attachment domain-containing protein.
 
 0.996
birA
biotin/acetyl-CoA-carboxylase ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family.
 
 
 0.881
ADQ04672.1
PFAM: biotin/lipoyl attachment domain-containing protein; KEGG: ate:Athe_1318 biotin/lipoyl attachment domain-containing protein.
 
  
 0.876
ADQ05653.1
PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: ate:Athe_2559 hypothetical protein.
 
  
 0.775
ADQ04145.1
PFAM: Transketolase central region; dehydrogenase E1 component; Transketolase domain-containing protein; KEGG: ate:Athe_0704 transketolase central region.
  
 
 0.737
ADQ04671.1
KEGG: ate:Athe_1317 hypothetical protein.
       0.729
ADQ04673.1
PFAM: Conserved carboxylase region; pyruvate carboxyltransferase; KEGG: ate:Athe_1319 conserved carboxylase region.
  
  
 0.688
ldh
L-lactate dehydrogenase; Catalyzes the conversion of lactate to pyruvate. Belongs to the LDH/MDH superfamily. LDH family.
  
  
 0.584
ADQ04676.1
PFAM: Phosphoglycerate mutase; KEGG: ate:Athe_1322 phosphoglycerate mutase.
  
   0.563
ADQ04586.1
PFAM: acyl-CoA dehydrogenase domain-containing protein; KEGG: ate:Athe_1232 acyl-CoA dehydrogenase domain protein.
 
 
 0.558
Your Current Organism:
Caldicellulosiruptor owensensis
NCBI taxonomy Id: 632518
Other names: C. owensensis OL, Caldicellulosiruptor owensensis DSM 13100, Caldicellulosiruptor owensensis OL, Caldicellulosiruptor owensensis str. OL, Caldicellulosiruptor owensensis strain OL
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