Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ADQ04672.1PFAM: biotin/lipoyl attachment domain-containing protein; KEGG: ate:Athe_1318 biotin/lipoyl attachment domain-containing protein. (127 aa)    
Predicted Functional Partners:
ADQ05519.1
PFAM: biotin/lipoyl attachment domain-containing protein; KEGG: csc:Csac_2483 biotin/lipoyl attachment domain-containing protein.
 
0.983
ADQ05518.1
Sodium ion-translocating decarboxylase, beta subunit; Tunnel subunit of the primary sodium pump glutaconyl-CoA decarboxylase (GCD).
 
 
 0.970
ADQ04670.1
PFAM: carboxyl transferase; KEGG: ate:Athe_1316 carboxyl transferase.
 
  
 0.876
ADQ04673.1
PFAM: Conserved carboxylase region; pyruvate carboxyltransferase; KEGG: ate:Athe_1319 conserved carboxylase region.
 
    0.875
ADQ04671.1
KEGG: ate:Athe_1317 hypothetical protein.
       0.776
birA
biotin/acetyl-CoA-carboxylase ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family.
 
   
 0.715
ispH
Hydroxymethylbutenyl pyrophosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family.
  
  
 0.702
ADQ05521.1
PFAM: Conserved carboxylase region; pyruvate carboxyltransferase; KEGG: csc:Csac_2485 hypothetical protein.
 
    0.641
guaA
GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP.
  
  
 0.632
ADQ04012.1
Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.
   
   0.625
Your Current Organism:
Caldicellulosiruptor owensensis
NCBI taxonomy Id: 632518
Other names: C. owensensis OL, Caldicellulosiruptor owensensis DSM 13100, Caldicellulosiruptor owensensis OL, Caldicellulosiruptor owensensis str. OL, Caldicellulosiruptor owensensis strain OL
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