Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ADQ04677.1PFAM: HutP family protein; KEGG: ate:Athe_1323 HutP family protein. (139 aa)    
Predicted Functional Partners:
ispH
Hydroxymethylbutenyl pyrophosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family.
 
     0.758
ADQ04678.1
Chorismate mutase; Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis.
       0.720
cmk
KEGG: ate:Athe_1325 cytidylate kinase; TIGRFAM: cytidylate kinase; PFAM: cytidylate kinase region; shikimate kinase.
       0.702
ADQ04676.1
PFAM: Phosphoglycerate mutase; KEGG: ate:Athe_1322 phosphoglycerate mutase.
       0.700
ADQ04680.1
KEGG: ate:Athe_1326 phospholipid/glycerol acyltransferase; PFAM: phospholipid/glycerol acyltransferase; SMART: phospholipid/glycerol acyltransferase.
       0.700
ADQ04674.1
KEGG: ate:Athe_1320 hypothetical protein.
 
     0.661
ADQ04675.1
Transcriptional regulator, RpiR family; PFAM: sugar isomerase (SIS); helix-turn-helix protein RpiR; KEGG: ate:Athe_1321 transcriptional regulator, RpiR family.
       0.650
ADQ04682.1
PFAM: PRC-barrel domain protein; KEGG: ate:Athe_1328 hypothetical protein.
       0.534
ADQ04683.1
KEGG: ate:Athe_1329 hypothetical protein.
       0.519
ADQ05235.1
PFAM: Coat F domain protein; KEGG: ate:Athe_1976 coat F domain protein.
  
     0.484
Your Current Organism:
Caldicellulosiruptor owensensis
NCBI taxonomy Id: 632518
Other names: C. owensensis OL, Caldicellulosiruptor owensensis DSM 13100, Caldicellulosiruptor owensensis OL, Caldicellulosiruptor owensensis str. OL, Caldicellulosiruptor owensensis strain OL
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